Genotoxicity, oxidative stress, and inflammatory response induced by crack-cocaine: Relevance to carcinogenesis

IT Malacarne, DV De Souza, BDA Rosario… - … science and pollution …, 2021 - Springer
Crack-cocaine is a cocaine by-product widely consumed by general population in
developing countries. The drug is low cost and is associated with more intense effects when …

Morphological and physiological changes in Tetrahymena pyriformis for the in vitro cytotoxicity assessment of Triton X-100

N Dias, RA Mortara, N Lima - Toxicology in vitro, 2003 - Elsevier
Non-ionic surfactants such as Triton X-100 have been widely used in industrial processing
and in cleaning products for almost 50 years, being effective and economic emulsifying …

[PDF][PDF] Tetrahymena spp.(Protista, Ciliophora) as test species in rapid multilevel ecotoxicity tests

A Gerhardt, A Ud-Daula, KW Schramm - Acta Protozoologica, 2010 - bibliotekanauki.pl
This review summarizes the application of Tetrahymena spp. in ecotoxicology, in order to
promote a more integrated, multi-level ecotoxicological assessment approach regarding the …

Immunotoxicity of cocaine and crack

M Stefanidou, A C. Loutsidou… - Current Drug Abuse …, 2011 - benthamdirect.com
The toxicity of cocaine and crack was studied on the protozoan Tetrahymena pyriformis,
using several endpoints, such as the DNA content of the macronuclei and the phagocytic …

DNA Content Alterations in Tetrahymena pyriformis Macronucleus after Exposure to Food Preservatives Sodium Nitrate and Sodium Benzoate

AC Loutsidou, VI Hatzi, CT Chasapis, GI Terzoudi… - Acta Biologica …, 2012 - Springer
The toxicity, in terms of changes in the DNA content, of two food preservatives, sodium
nitrate and sodium benzoate was studied on the protozoan Tetrahymena pyriformis using …

Effect of cocaine and crack on the ploidy status of Tetrahymena pyriformis: a study using DNA image analysis

ME Stefanidou, VI Hatzi, GI Terzoudi, AC Loutsidou… - Cytotechnology, 2011 - Springer
The effect of cocaine and crack on the ploidy status of Feulgen-stained Tetrahymena
pyriformis macronuclei using computerized DNA image analysis system was tested. For this …

DNA toxicity of cocaine hydrochloride and cocaine freebase by means of DNA image analysis on Tetrahymena pyriformis

M Stefanidou, A Chatziioannou, A Livaditou… - Biological and …, 2002 - jstage.jst.go.jp
MATERIALS AND METHODS A computerized image analysis system (CIAS), based on high-
resolution scanning, has proved to be an effective approach to examine and classify stained …

DNA content of Tetrahymena pyriformis as a biomarker for different toxic agents

M Stefanidou, G Alevizopoulos, C Spiliopoulou - Chemosphere, 2008 - Elsevier
The toxicity of different substances was studied on the protozoan Tetrahymena pyriformis,
using as an endpoint the DNA content of the macronucleus. Substances from various …

Automated image analysis to improve bead ingestion toxicity test counts in the protozoan Tetrahymena pyriformis

N Dias, AL Amaral, EC Ferreira… - Letters in applied …, 2003 - academic.oup.com
Aims: To improve bead ingestion counts in Tetrahymena pyriformis by automated image
analysis as an alternative to direct‐counts. Methods and Results: Fluorescent latex beads …

[PDF][PDF] Modulation of Phagocytosis in Tetrahymena thermophila by Histamine and the Antihistamine Diphenhydramine

N Buduma, J Balabanian, P Dalvi, SK Chia… - Acta …, 2013 - bibliotekanauki.pl
Histamine is a significant biological compound because of its role in mediating the human
allergic and inflammatory pathways. Antihistamines are often administered to control the …