Circulating tissue factor‐positive extracellular vesicles and their association with thrombosis in different diseases
Y Hisada, ATA Sachetto, N Mackman - Immunological reviews, 2022 - Wiley Online Library
Tissue factor (TF) is a procoagulant protein released from activated host cells, such as
monocytes, and tumor cells on extracellular vesicles (EVs). TF+ EVs are observed in the …
monocytes, and tumor cells on extracellular vesicles (EVs). TF+ EVs are observed in the …
Patients with COVID-19 have elevated levels of circulating extracellular vesicle tissue factor activity that is associated with severity and mortality—brief report
A Rosell, S Havervall, F von Meijenfeldt… - … and Vascular Biology, 2021 - Am Heart Assoc
Objective: Patients with coronavirus disease 2019 (COVID-19) have a high rate of
thrombosis. We hypothesized that severe acute respiratory syndrome coronavirus 2 infection …
thrombosis. We hypothesized that severe acute respiratory syndrome coronavirus 2 infection …
The kidney in hantavirus infection—epidemiology, virology, pathophysiology, clinical presentation, diagnosis and management
FC Koehler, V Di Cristanziano, MR Späth… - Clinical Kidney …, 2022 - academic.oup.com
Hantavirus-induced diseases are emerging zoonoses with endemic appearances and
frequent outbreaks in different parts of the world. In humans, hantaviral pathology is …
frequent outbreaks in different parts of the world. In humans, hantaviral pathology is …
Measurement of tissue factor-positive extracellular vesicles in plasma: strengths and weaknesses of current methods
N Mackman, ATA Sachetto… - Current Opinion in …, 2022 - journals.lww.com
We recommend isolating EVs from plasma and measuring TF activity using a functional
assay in the presence and absence of an anti-TF antibody. We do not recommend using …
assay in the presence and absence of an anti-TF antibody. We do not recommend using …
[HTML][HTML] Direct and indirect effects of Puumala hantavirus on platelet function
WC Schrottmaier, A Schmuckenschlager… - Thrombosis …, 2024 - Elsevier
Thrombocytopenia is a cardinal symptom of hantavirus-induced diseases including
Puumala virus (PUUV)-induced hemorrhagic fever with renal syndrome (HFRS), which is …
Puumala virus (PUUV)-induced hemorrhagic fever with renal syndrome (HFRS), which is …
Circulating extracellular vesicle tissue factor activity during orthohantavirus infection is associated with intravascular coagulation
Background Puumala orthohantavirus (PUUV) causes hemorrhagic fever with renal
syndrome (HFRS). Patients with HFRS have an activated coagulation system with increased …
syndrome (HFRS). Patients with HFRS have an activated coagulation system with increased …
Levels of peripheral blood routine, biochemical and coagulation parameters in patients with hemorrhagic fever with renal syndrome and their relationship with …
W Chen, H Du, H Hu, J Lian, H Jiang, J Li… - BMC Infectious …, 2024 - Springer
Abstract Background Hantaan virus (HTNV), Seoul virus (SEOV) and Puumala virus (PUUV)
are major serotypes of the Hantavirus, which can cause hemorrhagic fever with renal …
are major serotypes of the Hantavirus, which can cause hemorrhagic fever with renal …
Author Spotlight: High-Sensitivity Tissue Factor Activity Assay for Plasma Diagnosis
Y Hisada, N Mackman - JoVE (Journal of Visualized Experiments), 2023 - jove.com
Tissue factor (TF) is a transmembrane receptor for factor (F) VII and FVIIa. The TF/FVIIa
complex initiates the coagulation cascade by activating both FIX and FX. TF is released from …
complex initiates the coagulation cascade by activating both FIX and FX. TF is released from …