Microgravity protein crystallization

A McPherson, LJ DeLucas - npj Microgravity, 2015 - nature.com
Over the past 20 years a variety of technological advances in X-ray crystallography have
shortened the time required to determine the structures of large macromolecules (ie …

Macromolecular crystallization in microgravity

EH Snell, JR Helliwell - Reports on progress in physics, 2005 - iopscience.iop.org
Density difference fluid flows and sedimentation of growing crystals are greatly reduced
when crystallization takes place in a reduced gravity environment. In the case of …

Microgravity and macromolecular crystallography

CE Kundrot, RA Judge, ML Pusey… - Crystal Growth & …, 2001 - ACS Publications
Macromolecular crystal growth is seen as an ideal experiment to make use of the reduced
acceleration environment provided by an orbiting spacecraft. The experiments are small, are …

The physics of protein crystallization

PG Vekilov, AA Chernov - Solid State Physics, 2003 - Elsevier
Publisher Summary This chapter establishes a statistically viable correlation between the
available sequence of amino acids in the protein chain and the special folding of chain. This …

Microgravity as an environment for macromolecular crystallization–an outlook in the era of space stations and commercial space flight

EH Snell, JR Helliwell - Crystallography Reviews, 2021 - Taylor & Francis
In 2005 we reviewed microgravity for macromolecular crystallization, four years after the final
flight of the Space Shuttle Orbiter, and five years before the first commercial flight to the …

High-throughput screens for postgenomics: studies of protein crystallization using microsystems technology

G Juarez-Martinez, P Steinmann, AW Roszak… - Analytical …, 2002 - ACS Publications
This paper describes the fabrication of a micromachined miniaturized array of chambers in a
2-mm-thick single crystal〈 100∟ silicon substrate for the combinatorial screening of the …

[图书][B] Challenges of human space exploration

M Freeman - 2000 - books.google.com
For most people the Mir space station is synonymous with calamity-a fire, collision with an
unmanned Progress M-34 supply vehicle, and countless less life-threatening technical …

Physical aspects of protein crystal growth investigated with the Advanced Protein Crystallization Facility in reduced-gravity environments

A Vergara, B Lorber, A Zagari, R Giegé - … Crystallographica Section D …, 2003 - scripts.iucr.org
The physicochemical aspects of protein crystallization in reduced-gravity environments (µg)
have been investigated with the Advanced Protein Crystallization Facility during six space …

Lower dimer impurity incorporation may result in higher perfection of HEWL crystals grown in microgravity: A case study

DC Carter, K Lim, JX Ho, BS Wright, PD Twigg… - Journal of crystal …, 1999 - Elsevier
Crystals of tetragonal hen egg white lysozyme (HEWL) grown on a series of space missions
and their terrestrial counterparts were analyzed by gel electrophoresis and X-ray diffraction …

Interaction of coomassie brilliant blue G250 with human serum albumin: probing of the binding mechanism and binding site by spectroscopic and molecular modeling …

YS Li, YS Ge, Y Zhang, AQ Zhang, SF Sun… - Journal of Molecular …, 2010 - Elsevier
The interaction between coomassie brilliant blue G250 and human serum albumin was
investigated by spectroscopic methods such as fluorescence quenching, synchronous …