The idea that some phenotypes bear a closer relationship to the biological processes that
give rise to psychiatric illness than diagnostic categories has attracted considerable interest …

Schizophrenia (SZ) and bipolar disorder (BD) are debilitating neurobehavioural disorders
likely influenced by genetic and non-genetic factors and which can be seen as complex …

Objective: The authors used a custom array of 1,536 single-nucleotide polymorphisms
(SNPs) to interrogate 94 functionally relevant candidate genes for schizophrenia and identify …

Three linkage studies of bipolar disorder have implicated chromosome 12q24. 3 with lod
scores of over 3.0 and several other linkage studies have found lods between 2 and 3. Fine …

The glutamate neurotransmitter system is one of the major candidate pathways for the
pathophysiology of schizophrenia, and increased understanding of the pharmacology …

Numerous studies over the last several years have shown that d-amino acids, especially d-
serine, have been related to brain and neurological disorders. Acknowledged neurological …

Schizophrenia is a serious and disabling mental disorder with symptoms such as auditory
hallucinations, disordered thinking and delusions, avolition, anhedonia, blunted affect and …

OBJECTIVES: Based on the hypothesis of NMDA receptor hypofunction in schizophrenia,
plasma glycine, l-serine, and d-serine levels have been studied, since they could serve as …

MicroRNAs (miRNAs) are a class of endogenous and non-coding single-stranded RNAs of
approximately 22 nucleotides, many of which are evolutionarily conserved. Genome-wide …

The G72/G30 gene complex (G72 also known as D-amino acid oxidase activator, DAOA)
and its chromosomal region 13q32-34 have been linked and associated with both …