The present review aims to summarize the pharmacological profile of 1, 2, 4-triazole, one of
the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant …

The tyrosinase enzyme, which is widely found in microorganisms, animals and plants, has a
significant position in melanogenesis, plays an important role in undesirable browning of …

The chemistry of heterocyclic compounds has traditionally been and remains a bright area of
chemical science in Russia. This is due to the fact that many heterocycles find the widest …

Non-Steroidal biologically active heterocyclic compounds 4-(2-(4-chlorophenyl) benzo [d]
thiazol-3 (2H)-yl)-N-((3-substituted-2-hydrobenzo [d] thiazol-2-yl) methylene) thiazol-2 …

Twenty benzothiazole derivatives bearing a 1, 3, 4-oxadiazole moiety were synthesized and
evaluated for their anti-oxidant and anti-inflammatory activities. Among these compounds …

Benzothiazole, a fused heterocyclic moiety, has attracted synthetic and medicinal chemists
for good reasons. It is a valuable scaffold that possesses diverse biological activities, such …

We present a new efficient green synthetic protocol for introduction of substituents to the C-6
position of 2-arylbenzothiazole nuclei. Newly synthesized compounds were designed to …

The discovery of potent STAT3 inhibitors has gained noteworthy impetus in the last decade.
In line with this trend, considering the proven biological importance of 1, 2, 4-triazoles …

Cancer and oxidative stress are interrelated, with reactive oxygen species (ROS) playing
crucial roles in physiological processes and oncogenesis. Excessive ROS levels can induce …

Herein, we have carried out a structural optimization campaign to discover the novel anti-
tumor agents with our previously screened YQY-26 as the hit compound. A library of thirty …