Curcumin formulations for better bioavailability: what we learned from clinical trials thus far?

M Hegde, S Girisa, B BharathwajChetty, R Vishwa… - ACS …, 2023 - ACS Publications
Curcumin has been credited with a wide spectrum of pharmacological properties for the
prevention and treatment of several chronic diseases such as arthritis, autoimmune …

Improving curcumin bioavailability: Current strategies and future perspectives

R Tabanelli, S Brogi, V Calderone - Pharmaceutics, 2021 - mdpi.com
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is
also characterized by problematic drug delivery and scarce bioavailability, representing the …

Highly bioavailable forms of curcumin and promising avenues for curcumin-based research and application: a review

SJ Stohs, O Chen, SD Ray, J Ji, LR Bucci, HG Preuss - Molecules, 2020 - mdpi.com
Curcumin exerts a wide range of beneficial physiological and pharmacological activities,
including antioxidant, anti-amyloid, anti-inflammatory, anti-microbial, anti-neoplastic …

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

AB Kunnumakkara, D Bordoloi… - British journal of …, 2017 - Wiley Online Library
Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation

SW Ryter, AMK Choi - Translational Research, 2016 - Elsevier
The heme oxygenase-1 (HO-1) enzyme system remains an attractive therapeutic target for
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …

[HTML][HTML] Pharmacological mechanisms and clinical applications of curcumin: update

M Hao, Y Chu, J Lei, Z Yao, P Wang, Z Chen… - Aging and …, 2023 - ncbi.nlm.nih.gov
Curcumin, a well-known hydrophobic polyphenol extracted from the rhizomes of turmeric
(Curcuma longa L.), has attracted great interest in the last ten years due to its multiple …

Curcumin improves intestinal barrier function: modulation of intracellular signaling, and organization of tight junctions

J Wang, SS Ghosh, S Ghosh - American Journal of …, 2017 - journals.physiology.org
Association between circulating lipopolysaccharide (LPS) and metabolic diseases (such as
type 2 diabetes and atherosclerosis) has shifted the focus from high-fat high-cholesterol …

Curcumin supplementation and human disease: a scoping review of clinical trials

TM Panknin, CL Howe, M Hauer… - International Journal of …, 2023 - mdpi.com
Medicinal properties of turmeric (Curcuma longa L.), a plant used for centuries as an anti-
inflammatory, are attributed to its polyphenolic curcuminoids, where curcumin predominates …