Recent developments in chemical reactivity of N, N-dimethylenamino ketones as synthons for various heterocycles

HM Gaber, MC Bagley, ZA Muhammad, SM Gomha - RSC advances, 2017 - pubs.rsc.org
The current review presents recent progress in the utility of N, N-dimethyl enaminones as
building blocks for a diverse range of acyclic, carbocyclic, five-and six-membered …

[PDF][PDF] Dimethylformamide dimethyl acetal as a building block in heterocyclic synthesis

FA Abu‐Shanab, SM Sherif… - Journal of Heterocyclic …, 2009 - researchgate.net
N, N-dimethylformamide dimethyl acetal (DMFDMA)(1) is also called 1, 1-dimethoxy-N, N-
dimethylmethylamine and 1, 1-dimethoxytrimethylamine. The molecular formula (CH3) …

[HTML][HTML] Novel arylazo nicotinate derivatives as effective antibacterial agents: Green synthesis, molecular modeling, and structure-activity relationship studies

MR Eletmany, MA Albalawi, RAK Alharbi… - Journal of Saudi …, 2023 - Elsevier
A series of novel arylazo nicotinates compounds, denoted as (3a-k and 5a-d) were
synthesized and characterized through the reaction of 3-oxo-arylhydrazonals with various …

Synthesis, characterization and antitumor activity of novel tetrapodal 1, 4-dihydropyridines: p53 induction, cell cycle arrest and low damage effect on normal cells …

MF Mohamed, AF Darweesh, AHM Elwahy… - RSC …, 2016 - pubs.rsc.org
Synthesis of novel tetrakis (2, 6-dimethyl-4-phenyl-1, 4-dihydropyridinyl) methanes 5a–d by
acid-catalyzed condensation of the tetrakis-aldehydes 6a–d with eight equivalents of 3 …

[PDF][PDF] Enamines as precursors to polyfunctional heteroaromatic compounds; a decade of development

SM Riyadh, IA Abdelhamid, HM Al-Matar… - …, 2008 - triggered.edina.clockss.org
Recent synthesis and utilization of enamines as precursors for heterocyclic and carbocyclic
compounds are reviewed. Two general synthetic routes for preparation of enamines based …

Biological activities and docking studies on novel Bis 1, 4-DHPS linked to arene core via ether or ester linkage

NS Ibrahim, MF Mohamed, AHM Elwahy… - Letters in Drug …, 2018 - ingentaconnect.com
Background: Novel bis (1, 4-dihydropyridine) derivatives linked to arene core via ester 5-7
as well as ether linkages 10-12 were prepared, and their structures were confirmed by …

[PDF][PDF] Microwave assisted multi-component synthesis of novel bis (1, 4-dihydropyridines) based arenes or heteroarenes

SMH Sanad, RM Kassab, IA Abdelhamid… - …, 2016 - researchgate.net
A synthesis of novel bis-1, 4-DHPs was reported. Two possible synthetic approaches for
these compounds were investigated. In the first approach the monopodal 1, 4-DHPs were …

DBU-Catalyzed, facile and efficient method for synthesis of spirocyclic 2-oxindole derivatives with incorporated 6-amino-4H-pyridazines and fused derivatives via [3+ 3 …

IA Abdelhamid, MH Mohamed, AM Abdelmoniem… - Tetrahedron, 2009 - Elsevier
3-Cyanomethylidene oxindole derivatives were prepared in excellent yields utilizing DBU-
promoted Knoevenagel condensation of isatin derivatives with active methylene reagents …

Regioorientation in the Addition Reaction of α‐Substituted Cinnamonitrile to Enamines Utilizing Chitosan as a Green Catalyst: Unambiguous Structural …

SAS Ghozlan, AG Ahmed… - Journal of Heterocyclic …, 2016 - Wiley Online Library
Hexahydroquinolines and their fused derivatives are obtained in good to excellent yields by
proceeding through a simple, mild, and efficient procedure including the reaction of …

[PDF][PDF] Reactions of nitrilimines with heterocyclic amines and enamines. Convenient methodology for synthesis and annulation of heterocycles

AS Shawali, MM Edrees - Arkivoc, 2006 - arkat-usa.org
This review summarizes the reactions of nitrilimines, genearted in situ by base-catalyzed
dehydrohalogenation of the respective hydrazonoyl halides, with aminoazoles, aminoazines …