Cell-based drug delivery systems and their in vivo fate

L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

Emerging nanotechnological approaches to regulating tumor vasculature for cancer therapy

C Wang, J Xu, Y Zhang, G Nie - Journal of Controlled Release, 2023 - Elsevier
Abnormal angiogenesis stands for one of the most striking manifestations of malignant
tumor. The pathologically and structurally abnormal tumor vasculature facilitates a hostile …

Multifunctional AIE nanosphere-based “nanobomb” for trimodal imaging-guided photothermal/photodynamic/pharmacological therapy of drug-resistant bacterial …

B Li, W Wang, L Zhao, D Yan, X Li, Q Gao, J Zheng… - ACS …, 2023 - ACS Publications
Injudicious or inappropriate use of antibiotics has led to the prevalence of drug-resistant
bacteria, posing a huge menace to global health. Here, a self-assembled aggregation …

Engineered enzyme-loaded erythrocyte vesicles precisely deprive tumoral nutrients to induce synergistic near-infrared-II photothermal therapy and immune activation

C Nie, W Pan, B Wu, T Luo, J Lv, Y Fan, J Feng, C Liu… - ACS …, 2023 - ACS Publications
Starvation therapy has been considered a promising strategy in cancer treatment for altering
the tumor microenvironment (TME) and causing a cascade of therapeutic effects. However, it …

Red blood cell inspired strategies for drug delivery: emerging concepts and new advances

E Zhang, P Phan, HA Algarni, Z Zhao - Pharmaceutical Research, 2022 - Springer
In the past five decades, red blood cells (RBCs) have been extensively explored as drug
delivery systems due to their distinguishing potential in modulating the pharmacokinetic …

A red blood cell‐derived bionic microrobot capable of hierarchically adapting to five critical stages in systemic drug delivery

YX Zhu, HR Jia, YW Jiang, Y Guo, QY Duan… - …, 2024 - Wiley Online Library
The tumour‐targeting efficiency of systemically delivered chemodrugs largely dictates the
therapeutic outcome of anticancer treatment. Major challenges lie in the complexity of …

Red blood cells: a potential delivery system

M Chen, Y Leng, C He, X Li, L Zhao, Y Qu… - Journal of …, 2023 - Springer
Red blood cells (RBCs) are the most abundant cells in the body, possessing unique
biological and physical properties. RBCs have demonstrated outstanding potential as …

Covalent organic framework-derived carbonous nanoprobes for cancer cell imaging

P Gao, X Shen, X Liu, B Cui, M Wang… - … Applied Materials & …, 2021 - ACS Publications
Covalent organic frameworks (COFs) have emerged as promising materials for biomedical
applications, but their functions remain to be explored and the potential toxicity concerns …

Targeting tumor microenvironment with photodynamic nanomedicine

SK Modi, P Mohapatra, P Bhatt, A Singh… - Medicinal research …, 2025 - Wiley Online Library
Photodynamic therapy (PDT) is approved for the treatment of certain cancers and precancer
lesions. While early Photosensitizers (PS) have found their way to the clinic, research in the …

Living Cell‐Derived Intelligent Nanobots for Precision Oncotherapy

L Zhou, K Li, Y Liu, R Zhang, Y Yao… - Advanced Functional …, 2024 - Wiley Online Library
The progress of precision oncology medicine is always limited by the tumor off‐targeting, the
drug side effects, and the treatment inefficiency due to the complex and ever‐changing …