Haemoglobinopathies including the thalassemias and sickle cell disease are known to be
prevalent inherited disorders in most Arab countries with varying prevalence rates and …

Objectives To investigate the mutational spectrum in the HBB gene in Arab patients with β-
thal. Methods Authors searched five databases (PubMed, Science Direct, Scopus, Web of …

Thalassemia is one of the most prevalent genetic disorders worldwide. The present study
aimed to explore the mutational spectrum of all hemoglobin (HB) encoding genes and to …

The biomedical research sector in Saudi Arabia has recently received special attention from
the government, which is currently supporting research aimed at improving the …

Thalassemia is one of the most common single gene disorders worldwide. Nearly 80 to 90
million with minor beta thalassemia and 60–70 thousand affected infants are born annually …

Introduction: Detection of β-thalassemia trait or carriers (β-TT) depends significantly on an
increase in Hemoglobin A2 (HbA2) levels, which is found at low levels (< 3%) in normal …

Methods A cross-sectional study including adolescents and adults aged 14 years and above
with BTM treated in Almadinah Almunawwarah and excluding patients who had bone …

While previous studies from Iraq have focused on β-thalassemia (β-thal) mutations in the
northern part of the country, inhabited mainly by Kurds, no study of significance has looked …

Beta-thalassemia is a genetic disorder that is caused by variations in the beta-hemoglobin
(HBB) gene. Saudi Arabia is among the countries most affected by beta-thalassemia, and …

The concurrence of malaria and hemoglobinopathies, observed in malaria endemic regions,
reflects the phenomenon of natural selection. Since the life cycle of the malaria parasite has …