Tale of Twin Bifunctional Second Messenger (p) ppGpp Synthetases and Their Function in Mycobacteria

SK Sinha, N Rs, Y Devarakonda, A Rathi… - ACS …, 2023 - ACS Publications
M. tuberculosis, an etiological agent of tuberculosis, requires a long treatment regimen due
to its ability to respond to stress and persist inside the host. The second messenger (p) …

Control of transcriptional activity by design of charge patterning in the intrinsically disordered RAM region of the Notch receptor

KP Sherry, RK Das, RV Pappu… - Proceedings of the …, 2017 - National Acad Sciences
Intrinsically disordered regions (IDRs) play important roles in proteins that regulate gene
expression. A prominent example is the intracellular domain of the Notch receptor (NICD) …

SpoT Induces Intracellular Salmonella Virulence Programs in the Phagosome

LF Fitzsimmons, L Liu, S Kant, JS Kim, JK Till… - MBio, 2020 - Am Soc Microbiol
Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together
named (p) ppGpp, regulate diverse aspects of Salmonella pathogenesis, including synthesis …

Novel pppGpp binding site at the C‐terminal region of the Rel enzyme from Mycobacterium smegmatis

K Syal, H Joshi, D Chatterji, V Jain - The FEBS journal, 2015 - Wiley Online Library
Mycobacterium tuberculosis elicits the stringent response under unfavorable growth
conditions, such as those encountered by the pathogen inside the host. The hallmark of this …

[PDF][PDF] SpoT induces intracellular Salmonella virulence programs in the phagosome. mBio 11: e03397-19

LF Fitzsimmons, L Liu, S Kant, JS Kim, JK Till… - 2020 - academia.edu
Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together
named (p) ppGpp, regulate diverse aspects of Salmonella pathogenesis, including synthesis …

[图书][B] Nucleotide Metabolism in Salmonella Pathogenesis

LF Fitzsimmons - 2018 - search.proquest.com
Entereopathogenic Salmonella cause debilitating diseases in millions of people every year
worldwide. As antibiotic treatments for Salmonella fail due to increased prevalence of …

[PDF][PDF] Exploring the role of the stringent response in Mycobacterium tuberculosis dormancy

AL Ellison - 2018 - jscholarship.library.jhu.edu
Mycobacterium tuberculosis is the leading cause of death by an infectious disease and
remains one of the top overall causes of mortality worldwide. With antibiotic resistance rising …

Elucidating the Molecular Details of RssB-Mediated Turnover of σS by the AAA+ Protease, ClpXP and its Inhibition by Anti-Adaptors

JE Zammit - 2018 - opal.latrobe.edu.au
Submission note: A thesis submitted in total fulfilment of the requirements for the degree of
Doctor of Philosophy to the Department of Biochemistry and Genetics, School of Molecular …

Quarterly intrinsic disorder digest (April–May–June, 2014)

S DeForte, VN Uversky - Intrinsically Disordered Proteins, 2017 - Taylor & Francis
This is the 6th issue of the Digested Disorder series that continues to use only 2 criteria for
inclusion of a paper to this digest: The publication date (a paper should be published within …

[引用][C] Shelly DeForte

V Uversky