Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

The array of whiskers on the snout provides rodents with tactile sensory information relating
to the size, shape and texture of objects in their immediate environment. Rodents can use …

Hyper-reactivity to sensory input is a common and debilitating symptom in individuals with
autism spectrum disorders (ASD), but the neural basis underlying sensory abnormality is not …

Neural computation involves diverse types of GABAergic inhibitory interneurons that are
integrated with excitatory (E) neurons into precisely structured circuits. To understand how …

How learning enhances neural representations for behaviorally relevant stimuli via activity
changes of cortical cell types remains unclear. We simultaneously imaged responses of …

Neocortex is classically divided into distinct areas, each specializing in different function, but
all could benefit from reinforcement feedback to inform and update local processing. Yet it …

Mouse primary somatosensory barrel cortex (wS1) processes whisker sensory information,
receiving input from two distinct thalamic nuclei. The first-order ventral posterior medial …

The concept of a dynamic excitation/inhibition balance tuned by circuit disinhibition, which
can shape information flow during complex behavioral tasks, has arisen as an important and …

A surprising finding of recent studies in mouse is the dominance of widespread movement-
related activity throughout the brain, including in early sensory areas. In awake subjects …

The neocortex is functionally organized into layers. Layer four receives the densest bottom
up sensory inputs, while layers 2/3 and 5 receive top down inputs that may convey predictive …