The dairy industry has focused on maximizing milk yield, as it is believed that this maximizes
profit mainly through dilution of maintenance costs. Efficiency of milk production has …

Large-scale epidemiological studies show that low exercise capacity is the highest risk
factor for all-cause morbidity and mortality relative to other conditions including diabetes …

Maximal exercise-associated oxidative capacity is strongly correlated with health and
longevity in humans. Rats selectively bred for high running capacity (HCR) have improved …

Aims Observational evidence suggests that physical activity (PA) is inversely and
sedentarism positively related with cardiovascular disease risk. We performed a two-sample …

The gut microbiota is considered a relevant factor in obesity and associated metabolic
diseases, for which postmenopausal women are particularly at risk. Increasing physical …

Objective Cardiorespiratory fitness (CRF) is tightly linked with health and longevity and is
implicated in metabolic flexibility and substrate metabolism. The high capacity runner (HCR) …

Metabolic syndrome is a complex disorder that comprises several other complex disorders,
including obesity, hypertension, dyslipidemia, and diabetes. There are several rat models …

The intrinsic aerobic capacity of an organism is thought to play a role in aging and longevity.
Maximal respiratory rate capacity, a metabolic performance measure, is one of the best …

Key points Low intrinsic aerobic capacity is associated with increased all‐cause and liver‐
related mortality in humans. Low intrinsic aerobic capacity in the low capacity runner (LCR) …

High aerobic endurance capacity can be acquired by training and/or inherited. Aerobic
exercise training (AET) and aging are linked to altered gut microbiome composition, but it is …