Oxidative stress in neurodegenerative diseases
E Niedzielska, I Smaga, M Gawlik, A Moniczewski… - Molecular …, 2016 - Springer
The pathophysiologies of neurodegenerative diseases, including amyotrophic lateral
sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD), are far from being …
sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD), are far from being …
Prying into the prion hypothesis for Parkinson's disease
In Parkinson's disease, intracellular α-synuclein inclusions form in neurons. We suggest that
prion-like behavior of α-synuclein is a key component in Parkinson's disease pathogenesis …
prion-like behavior of α-synuclein is a key component in Parkinson's disease pathogenesis …
[HTML][HTML] The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases
Olfactory deficits are present in numerous neurodegenerative disorders and are
accompanied by pathology in related brain regions. In several of these disorders, olfactory …
accompanied by pathology in related brain regions. In several of these disorders, olfactory …
Naringenin alleviates paraquat-induced dopaminergic neuronal loss in SH-SY5Y cells and a rat model of Parkinson's disease
Abstract Parkinson's disease (PD), a common neurodegenerative disease is characterized
by the progressive loss of dopaminergic neurons in the substantia nigra. The cause of …
by the progressive loss of dopaminergic neurons in the substantia nigra. The cause of …
Curcumin affords neuroprotection and inhibits α-synuclein aggregation in lipopolysaccharide-induced Parkinson's disease model
N Sharma, B Nehru - Inflammopharmacology, 2018 - Springer
Parkinson's disease (PD) pathology is characterized by the abnormal accumulation and
aggregation of the pre-synaptic protein α-synuclein in the dopaminergic neurons as Lewy …
aggregation of the pre-synaptic protein α-synuclein in the dopaminergic neurons as Lewy …
Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress
M Akbar, MM Essa, G Daradkeh, MA Abdelmegeed… - Brain research, 2016 - Elsevier
Mitochondria are important for providing cellular energy ATP through the oxidative
phosphorylation pathway. They are also critical in regulating many cellular functions …
phosphorylation pathway. They are also critical in regulating many cellular functions …
Taurine protects dopaminergic neurons in a mouse Parkinson's disease model through inhibition of microglial M1 polarization
Y Che, L Hou, F Sun, C Zhang, X Liu, F Piao… - Cell death & …, 2018 - nature.com
Microglia-mediated neuroinflammation is implicated in multiple neurodegenerative
disorders, including Parkinson's disease (PD). Hence, the modulatioein of sustained …
disorders, including Parkinson's disease (PD). Hence, the modulatioein of sustained …
[HTML][HTML] Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model
L Hou, F Sun, R Huang, W Sun, D Zhang, Q Wang - Redox biology, 2019 - Elsevier
The activation of NADPH oxidase contributes to dopaminergic neurodegeneration and
motor deficits in Parkinson's disease (PD). However, whether NADPH oxidase is involved in …
motor deficits in Parkinson's disease (PD). However, whether NADPH oxidase is involved in …
NADPH oxidase regulates paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis
L Hou, R Huang, F Sun, L Zhang, Q Wang - Toxicology, 2019 - Elsevier
The activation of NADPH oxidase contributes to dopaminergic neurodegeneration induced
by paraquat and maneb, two concurrently used pesticides in agriculture. However, the …
by paraquat and maneb, two concurrently used pesticides in agriculture. However, the …
[HTML][HTML] Multifactorial theory applied to the neurotoxicity of paraquat and paraquat-induced mechanisms of developing Parkinson's disease
X Zhang, M Thompson, Y Xu - Laboratory investigation, 2016 - Elsevier
Laboratory studies involving repeated exposure to paraquat (PQ) in different animal models
can induce many of the pathological features of Parkinson's disease (PD), such as the loss …
can induce many of the pathological features of Parkinson's disease (PD), such as the loss …