The β Subunit of Voltage-Gated Ca2+ Channels

Z Buraei, J Yang - Physiological reviews, 2010 - journals.physiology.org
Calcium regulates a wide spectrum of physiological processes such as heartbeat, muscle
contraction, neuronal communication, hormone release, cell division, and gene …

Cannabinoid CB1 receptors control conditioned drug seeking

TJ De Vries, ANM Schoffelmeer - Trends in pharmacological sciences, 2005 - cell.com
Recent developments have implicated cannabinoid CB 1 receptors as a novel target for a
new class of therapeutic agents used to treat drug addiction. CB 1 receptors are expressed …

Presynaptic Ca2+ channels–integration centers for neuronal signaling pathways

RM Evans, GW Zamponi - Trends in neurosciences, 2006 - cell.com
Calcium influx into presynaptic nerve terminals via voltage-gated Ca 2+ channels is an
essential step in neurotransmitter release. The predominant Ca 2+ channel species in …

Ca2+ channel β-subunits: structural insights AID our understanding

MW Richards, AJ Butcher, AC Dolphin - Trends in pharmacological …, 2004 - cell.com
It has taken 17 years from the first identification of a voltage-gated Ca 2+ channel (Ca V) β-
subunit as a band on a gel following purification of skeletal muscle dihydropyridine (DHP) …

Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy

A Tadmouri, S Kiyonaka, M Barbado, M Rousset… - The EMBO …, 2012 - embopress.org
Calcium current through voltage‐gated calcium channels (VGCC) controls gene expression.
Here, we describe a novel signalling pathway in which the VGCC Cacnb4 subunit directly …

Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for β1 but not for palmitoylated β2, implicating an additional binding site in the …

J Leroy, MS Richards, AJ Butcher… - Journal of …, 2005 - Soc Neuroscience
The CaVβ subunits of voltage-gated calcium channels regulate these channels in several
ways. Here we investigate the role of these auxiliary subunits in the expression of functional …

Opioid receptor regulation of neuronal voltage-gated calcium channels

N Weiss, GW Zamponi - Cellular and Molecular Neurobiology, 2021 - Springer
Neuronal voltage-gated calcium channels play a pivotal role in the conversion of electrical
signals into calcium entry into nerve endings that is required for the release of …

How do G proteins directly control neuronal Ca2+ channel function?

M De Waard, J Hering, N Weiss, A Feltz - Trends in pharmacological …, 2005 - cell.com
Ca 2+ entry into neuronal cells is modulated by the activation of numerous G-protein-
coupled receptors (GPCRs). Much effort has been invested in studying direct G-protein …

[HTML][HTML] Cav2. 3 R-type voltage-gated Ca2+ channels-functional implications in convulsive and non-convulsive seizure activity

C Wormuth, A Lundt, C Henseler, R Müller… - The open neurology …, 2016 - ncbi.nlm.nih.gov
Background: Researchers have gained substantial insight into mechanisms of synaptic
transmission, hyperexcitability, excitotoxicity and neurodegeneration within the last decades …

Molecular Regulation of Voltage-Gated Ca2+ Channels

R Felix - Journal of receptors and Signal Transduction, 2005 - Taylor & Francis
Voltage-gated Ca2+ (CaV) channels are found in all excitable cells and many nonexcitable
cells, in which they govern Ca2+ influx, thereby contributing to determine a host of important …