Mapping tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …

Purpose To investigate the relationship between transverse relaxation rates R2 and R2*, the
most frequently used surrogate markers for iron in brain tissue, and chemically determined …

One objective of modern neuroimaging is to identify markers that can aid in diagnosis,
disease progression monitoring and long-term drug impact analysis. In this study, Parkinson …

Traumatic brain injury (TBI) is a structural and physiological disruption of brain function
caused by external forces. It is a major cause of death and disability for patients worldwide …

Iron is important for brain oxygen transport, electron transfer, neurotransmitter synthesis, and
myelin production. Though iron deposition has been observed in the brain with normal …

Phantoms, both numerical (software) and physical (hardware), can serve as a gold standard
for the validation of MRI methods probing the brain microstructure. This review aims to …

Diffusion tensor imaging (DTI) of the brain has become a mainstay in the study of normal
aging of white matter, and only recently has attention turned to the use of DTI to examine …

Iron is considered to play a key role in the development and progression of Multiple
Sclerosis (MS). In particular, iron that accumulates in myeloid cells after the blood-brain …

Objective. Brain iron deficiency has been supposed to be involved in the pathophysiology of
ADHD. Available studies assessing iron in ADHD are based on serum ferritin, a peripheral …