Oligodendrocyte precursor cells (OPCs) originate in the ventricular zones (VZs) of the brain
and spinal cord and migrate throughout the developing central nervous system (CNS) …

Malignant brain tumors strike deep into the psyche of those receiving and those delivering
the diagnosis. Malignant gliomas, the most common subtype of primary brain tumors, are …

Multiple sclerosis is a common cause of neurological disability in young adults. The disease
is complex—its aetiology is multifactorial and largely unknown; its pathology is …

Some proclaim that the major principles of development tors such as hormones, however,
influence final organ are now understood (Wolpert, 1996). Yet one of the most size. Growth …

Oligodendrocytes and the myelin they produce are a remarkable vertebrate specialization
that enables rapid and efficient nerve conduction within the central nervous system. The …

Strict control of cellular proliferation is required to shape the complex structures of the
developing embryo. The organ of Corti, the auditory neuroepithelium of the inner ear in …

The G1 phase of the cell cycle of neuroepithelial cells, the progenitors of all neurons of the
mammalian central nervous system, has been known to lengthen concomitantly with the …

We have discovered that intracellular redox state appears to be a necessary and sufficient
modulator of the balance between self-renewal and differentiation in dividing …

The duration of infection and the quantity of Ag presented in vivo are commonly assumed to
influence, if not determine, the magnitude of T cell responses. Although the cessation of in …

In the cellular program leading to DNA synthesis, signals that drive cells into S-phase
converge at the level of CDK activity. The products of at least three different gene families …