Biological Versus Chronological Aging: JACC Focus Seminar

MR Hamczyk, RM Nevado, A Barettino, V Fuster… - Journal of the American …, 2020 - jacc.org
Aging is the main risk factor for vascular disease and ensuing cardiovascular and
cerebrovascular events, the leading causes of death worldwide. In a progressively aging …

Vascular aging: assessment and intervention

A Li, J Yan, Y Zhao, Z Yu, S Tian, AH Khan… - … Interventions in Aging, 2023 - Taylor & Francis
Vascular aging represents a collection of structural and functional changes in a blood vessel
with advancing age, including increased stiffness, vascular wall remodeling, loss of …

Effects of adult growth hormone deficiency and replacement therapy on the cardiometabolic risk profile

B Ratku, V Sebestyén, A Erdei, EV Nagy, Z Szabó… - Pituitary, 2022 - Springer
Adult growth hormone deficiency (AGHD) is considered a rare endocrine disorder involving
patients with childhood-onset and adult-onset growth hormone deficiency (AoGHD) and …

Birth weight predicts aging trajectory: A hypothesis

AM Vaiserman - Mechanisms of ageing and development, 2018 - Elsevier
Increasing evidence suggests that risk for age-related disease and longevity can be
programmed early in life. In human populations, convincing evidence has been …

The relationship between telomere length and putative markers of vascular ageing: a systematic review and meta-analysis

M Kosmopoulos, M Chiriaco, K Stamatelopoulos… - Mechanisms of Ageing …, 2022 - Elsevier
Accelerated biological aging contributes to the evolution of cardiovascular disease.
However, its influence on subclinical organ damage remains unclear. Leukocyte telomere …

Telomere shortening associates with elevated insulin and nuchal fat accumulation

H Mangge, M Herrmann, G Almer, S Zelzer… - Scientific Reports, 2020 - nature.com
Obesity and relative leucocyte telomere length (RTL) are both linked to accelerated aging
and premature mortality. We examined if nuchal subcutaneous adipose tissue (SAT) …

An update in toxicology of ageing

L Rackova, M Mach, Z Brnoliakova - Environmental Toxicology and …, 2021 - Elsevier
The field of ageing research has been rapidly advancing in recent decades and it had
provided insight into the complexity of ageing phenomenon. However, as the organism …

Why should growth hormone (GH) be considered a promising therapeutic agent for arteriogenesis? Insights from the GHAS trial

D Caicedo, P Devesa, CV Alvarez, J Devesa - Cells, 2020 - mdpi.com
Despite the important role that the growth hormone (GH)/IGF-I axis plays in vascular
homeostasis, these kind of growth factors barely appear in articles addressing the …

Impact of premature coronary artery disease on adverse event risk following first percutaneous coronary intervention

TH Pinxterhuis, EH Ploumen, P Zocca… - Frontiers in …, 2023 - frontiersin.org
Objectives We assessed differences in risk profile and 3-year outcome between patients
undergoing percutaneous coronary intervention (PCI) for premature and non-premature …

Association between Growth Differentiation Factor‐15 and Risk of Cardiovascular Diseases in Patients with Adult Growth Hormone Deficiency

X Wu, Y Wang, Z Ren, L Li, W Qian… - International Journal …, 2021 - Wiley Online Library
Objective. Patients with adult growth hormone deficiency (AGHD) confer a heightened risk of
cardiovascular disease and increased mortality because of metabolic disorders. Growth …