The characterization of germline genetic variation affecting cancer risk, known as cancer
predisposition, is fundamental to preventive and personalized medicine. Studies of genetic …

Identical genetic variations can have different phenotypic effects depending on their parent
of origin. Yet, studies focusing on parent-of-origin effects have been limited in terms of …

Background Telomeres are repetitive DNA sequences located at the ends of chromosomes,
playing a vital role in maintaining chromosomal integrity and stability. Dysregulation of …

Introduction: Genome-wide association studies have identified that genetic polymorphisms
in the telomerase reverse transcrip-tase (TERT) and cleft lip and palate transmembrane 1 …

Materials and Methods: This case–control association study conducted at the Shri Mata
Vaishno Devi University, includes 150 breast, 150 ovarian cancer cases, and 210 healthy …

Colorectal cancer (CRC), which includes the development of cancer from the colon or
rectum, is one of the highly prevalent cancers in the populations of Jammu and Kashmir …

Purpose Lung cancer is a malignant tumor with obvious genetic predisposition. Association
studies have proposed that rs2853677, a SNP localizing at intron region of TERT …

Methods: A total of 93 patients, including 18 males and 73 females, who were clinically and
histopathologically diagnosed with sarcoidosis were included in the study. The 78 patients …

Background Non-small cell lung cancer (NSCLC) is the most common lung cancer,
accounting for 80–85% of all lung cancer cases. Various genetic studies have associated …

Genetic instabilities exacerbated by the dysfunction of telomeres can lead to the
development of cancer. Nearly 90% of all human malignancies are linked with telomere …