Infantile spasms (IS or epileptic spasms during infancy) were first described by Dr. William
James West (aka West syndrome) in his own son in 1841. While rare by definition (occurring …

Objectives Considering the dearth of literature on West syndrome (WS) from South Asian
countries, this study aimed to evaluate the management practices in South Asia by an online …

Purpose To assess epilepsy, motor function, cognitive, sleep, and quality of life outcomes
and their predictors in a follow-up cohort with West syndrome (WS) at≥ 5 years of age …

Infantile spasms are the defining seizures of West syndrome, a severe form of early life
epilepsy with poorly-understood pathophysiology. We present a novel comparative analysis …

Background and objectives The existing literature indicates a higher risk of mortality among
children with Infantile epileptic spasms syndrome (IESS). Our aim was to find the mortality …

Background The intestinal flora (IF) regulates brain function via the neuroendocrine and
neuroimmune systems and influences the development of several neuropsychiatric …

Infantile spasms (ISs) is a devastating form of an early infantile epileptic encephalopathy.
The patterns of response of multiple regimens, and the difference in response rates for the …

Purpose To describe the management of infants with epileptic spasms (ESs) in a low-
income country and identify factors predictive of their prognosis. Material and methods We …

Objective Infantile spasms is an epileptic encephalopathy of childhood, and its
pathophysiology is largely unknown. We generated a heterozygous knock‐in mouse with …

Infantile spasms remain the most challenging of the epileptic encephalopathies of
childhood. Infantile spasms are classified as an epileptic encephalopathy, as the adverse …