Sepsis is a severe medical condition characterized by a systemic inflammatory response,
often culminating in multiple organ dysfunction and high mortality rates. In recent years …

Background Recent studies have reported that preadmission metformin users had lower
mortality than non-metformin users in patients with sepsis and diabetes mellitus; however …

The safety and efficacy of anti-diabetic drugs are critical for maximizing the beneficial
impacts of well-controlled blood glucose on the prognosis of individuals with COVID-19 and …

Background: Sepsis is a deadly disease worldwide. Effective treatment strategy of sepsis
remains limited. There still was a controversial about association between preadmission …

Objective The Lactate-to-Albumin Ratio (LAR) has been applied as a new predictor in
sepsis, heart failure, and acute respiratory failure. However, the role of LAR in predicting all …

Metformin, a widely used antihyperglycaemic, has a good safety profile, reasonably
manageable side‐effects, is inexpensive, and causes a desirable amount of weight loss. In 4 …

Despite advances in sepsis management, it remains a major intensive-care-unit (ICU)
concern. From new prospective, positive effects of metformin, such as anti-oxidant and anti …

OBJECTIVES: Whether metformin exposure is associated with improved outcomes in
patients with type 2 diabetes mellitus and sepsis. DESIGN: Retrospective cohort study …

Introduction Diabetes mellitus is one of the most prevalent comorbidities identified in
patients with coronavirus disease 2019 (COVID-19). This article aims to discuss the …

Background: Metformin-associated lactic acidosis (MALA) is a severe complication of drug
administration with significant morbidity and mortality. So far no study in large population …