Understanding mechanisms of antioxidant action in health and disease

B Halliwell - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

Phytochemicals in cancer treatment: From preclinical studies to clinical practice

AS Choudhari, PC Mandave, M Deshpande… - Frontiers in …, 2020 - frontiersin.org
Cancer is a severe health problem that continues to be a leading cause of death worldwide.
Increasing knowledge of the molecular mechanisms underlying cancer progression has led …

[HTML][HTML] Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence

R Kotecha, A Takami, JL Espinoza - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cancer chemoprevention involves the use of different natural or biologic agents to inhibit or
reverse tumor growth. Epidemiological and pre-clinical data suggest that various natural …

Current evidence on the effect of dietary polyphenols intake on chronic diseases

C Costa, A Tsatsakis, C Mamoulakis, M Teodoro… - Food and Chemical …, 2017 - Elsevier
Polyphenols are secondary metabolites of plants. They comprise several antioxidant
compounds and they are generally considered to be involved in the defense against human …

The benefits and risks of certain dietary carotenoids that exhibit both anti-and pro-oxidative mechanisms—A comprehensive review

HS Black, F Boehm, R Edge, TG Truscott - Antioxidants, 2020 - mdpi.com
Carotenoid pigments, particularly β-carotene and lycopene, are consumed in human
foodstuffs and play a vital role in maintaining health. β-carotene is known to quench singlet …

Phytotherapeutics in cancer invasion and metastasis

B Salehi, P Zucca, M Sharifi‐Rad… - Phytotherapy …, 2018 - Wiley Online Library
Cancer is a multifactorial disease, and therefore, a multitarget approach is needed to face
the complex cancer biology, based on the combined use of different natural and synthetic …

Anti-prostate cancer protection and therapy in the framework of predictive, preventive and personalised medicine—comprehensive effects of phytochemicals in …

A Mazurakova, M Samec, L Koklesova, K Biringer… - EPMA Journal, 2022 - Springer
According to the GLOBOCAN 2020, prostate cancer (PCa) is the most often diagnosed male
cancer in 112 countries and the leading cancer-related death in 48 countries. Moreover …

Date (Phoenix dactylifera) Polyphenolics and Other Bioactive Compounds: A Traditional Islamic Remedy's Potential in Prevention of Cell Damage, Cancer …

BR Yasin, HAN El-Fawal, SA Mousa - International journal of molecular …, 2015 - mdpi.com
This review analyzes current studies of the therapeutic effects of Phoenix dactylifera, or date
palm fruit, on the physiologic system. Specifically, we sought to summarize the effects of its …

Inhibition of Cancer Development by Natural Plant Polyphenols: Molecular Mechanisms

A Lyubitelev, V Studitsky - International Journal of Molecular Sciences, 2023 - mdpi.com
Malignant tumors remain one of the main sources of morbidity and mortality around the
world. A chemotherapeutic approach to cancer treatment poses a multitude of challenges …

Phytochemicals as adjunctive with conventional anticancer therapies

M Hosein Farzaei, R Bahramsoltani… - Current …, 2016 - ingentaconnect.com
Background: Cancer is defined as the abnormal proliferations of cells which could occur in
any tissue and can cause life-threatening malignancies with high financial costs for both …