Macrolide antibiotics are macrocyclic compounds that are clinically used and prescribed for
the treatment of upper and lower respiratory tract infections. They inhibit the synthesis of …

Background: Invasive fungal infections (IFIs) are primarily caused by Candida spp.,
Cryptococcus neoformans, Aspergillus spp., Mucor spp., Sporothrix spp., and Pneumocystis …

In this work, we report the isolation and detailed functional characterization for the new non-
ribosomally synthesized antibiotic 5812-A/C, which was derived from metabolites of …

We report a novel family of natural lipoglycopeptides produced by Streptomyces sp. INA‐Ac‐
5812. Two major components of the mixture, named gausemycins A and B, were isolated …

Chemical screening of Streptomyces sp. NRRL S-4 with liquid chromatography–mass
spectrometry (LC–MS) and the following chromatographic isolation led to the discovery of …

Irumamycin (Iru) is a complex polyketide with pronounced antifungal activity produced by a
type I polyketide (PKS) synthase. Iru features a unique hemiketal ring and an epoxide group …

Background In recent years, new drugs for the treatment of various diseases, thereby the
emergence of antimicrobial resistance tremendously increased because of the increased …

РЕФЕРАТ Метою даної кваліфікаційної роботи є розробка апаратурної та технологічної
схеми біосинтезу вторинного метаболіту фунгіциду розеофунгіну з використанням …