Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

The emerging and re-emerging viral diseases are continuous threats to the wellbeing of
human life. Previous outbreaks of Severe Acute Respiratory Syndrome (SARS) and Middle …

The N-terminal fusion peptide (residues 770–788) of an S2 glycoprotein of the severe acute
respiratory syndrome coronavirus (SARS-CoV), exposed upon receptor binding, is crucial …

Cholesterol is a critical component of mammalian cell membranes and an allosteric
modulator of G protein-coupled receptors (GPCRs), but divergent views exist on the …

The organization and function of the serotonin1A receptor, an important member of the
GPCR family, have been shown to be cholesterol-dependent, although the molecular …

The realization that the lipid environment is crucial for maintaining the structure and function
of membrane proteins prompts new methods to understand lipid interactions. One such …

The questions of whether G protein-coupled receptors exist as monomers, dimers, and/or
oligomers and if these species interconvert in a ligand-dependent manner are among the …

N-terminal residues (770–788) of the S2 glycoprotein of severe acute respiratory syndrome
coronavirus (SARS-CoV) have been recognized as a potential fusion peptide that can be …

Oxytocin mediates its behavioural effects via the centrally expressed oxytocin receptor
(OTR). Oxytocin signalling has been implicated in multiple disorders involving centrally …

The extensive experimental and computational evidences revealed that cholesterol is
involved in the drug binding to G protein-coupled receptor (GPCR) targets that is influenced …