Biofilm dispersion

KP Rumbaugh, K Sauer - Nature Reviews Microbiology, 2020 - nature.com
The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …

Cyclic di-GMP: second messenger extraordinaire

U Jenal, A Reinders, C Lori - Nature Reviews Microbiology, 2017 - nature.com
Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various
important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di …

The non-attached biofilm aggregate

KN Kragh, T Tolker-Nielsen, M Lichtenberg - Communications Biology, 2023 - nature.com
Biofilms have conventionally been perceived as dense bacterial masses on surfaces,
following the five-step model of development. Initial biofilm research focused on surface …

Understanding, monitoring, and controlling biofilm growth in drinking water distribution systems

S Liu, C Gunawan, N Barraud, SA Rice… - … science & technology, 2016 - ACS Publications
In drinking water distribution systems (DWDS), biofilms are the predominant mode of
microbial growth, with the presence of extracellular polymeric substance (EPS) protecting …

Cyclic di-GMP: the first 25 years of a universal bacterial second messenger

U Römling, MY Galperin… - … and Molecular Biology …, 2013 - Am Soc Microbiol
Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

The Wsp system of Pseudomonas aeruginosa links surface sensing and cell envelope stress

L O'Neal, C Baraquet, Z Suo… - Proceedings of the …, 2022 - National Acad Sciences
Surface sensing is a critical process that promotes the transition to a biofilm lifestyle. Several
surface-sensing mechanisms have been described for a range of species, most involving …

Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles

SL Chua, Y Liu, JKH Yam, Y Chen, RM Vejborg… - Nature …, 2014 - nature.com
Bacteria assume distinct lifestyles during the planktonic and biofilm modes of growth.
Increased levels of the intracellular messenger c-di-GMP determine the transition from …

Regulation of biofilm formation in Pseudomonas and Burkholderia species

M Fazli, H Almblad, ML Rybtke… - Environmental …, 2014 - Wiley Online Library
In the present review, we describe and compare the molecular mechanisms that are
involved in the regulation of biofilm formation by P seudomonas putida, P seudomonas …

Engineering a microbial 'trap and release'mechanism for microplastics removal

SY Liu, MML Leung, JKH Fang, SL Chua - Chemical Engineering Journal, 2021 - Elsevier
Plastics are discarded and accumulated in the environment at an alarming rate. However,
their resistance to biodegradation allows them to persist in the environment for prolonged …

Persistent Bacterial Coinfection of a COVID-19 Patient Caused by a Genetically Adapted Pseudomonas aeruginosa Chronic Colonizer

J Qu, Z Cai, Y Liu, X Duan, S Han, J Liu… - Frontiers in cellular …, 2021 - frontiersin.org
Pseudomonas aeruginosa is a biofilm-forming opportunistic pathogen which causes chronic
infections in immunocompromised patients and leads to high mortality rate. It is identified as …