Extracellular membrane vesicles in the three domains of life and beyond

S Gill, R Catchpole, P Forterre - FEMS microbiology reviews, 2019 - academic.oup.com
Cells from all three domains of life, Archaea, Bacteria and Eukarya, produce extracellular
vesicles (EVs) which are sometimes associated with filamentous structures known as …

Extracellular vesicle biogenesis and functions in gram-positive bacteria

P Briaud, RK Carroll - Infection and immunity, 2020 - Am Soc Microbiol
Extracellular vesicles (EVs) are membrane-derived lipid bilayers secreted by bacteria and
eukaryotic cells. Bacterial membrane vesicles were discovered over 60 years ago and have …

hucMSC derived exosomes promote functional recovery in spinal cord injury mice via attenuating inflammation

G Sun, G Li, D Li, W Huang, R Zhang, H Zhang… - Materials Science and …, 2018 - Elsevier
The exploration of effective spinal cord injury (SCI) healing still remain a great challenge
due to the high morbidity, complex pathology and unclear targets. Human umbilical cord …

Role of exosomes in central nervous system diseases

W Liu, X Bai, A Zhang, J Huang, S Xu… - Frontiers in molecular …, 2019 - frontiersin.org
There are many types of intercellular communication, and extracellular vesicles are one of
the important forms of this. They are released by a variety of cell types, are heterogeneous …

Inclusion biogenesis, methods of isolation and clinical application of human cellular exosomes

M Tschuschke, I Kocherova, A Bryja… - Journal of clinical …, 2020 - mdpi.com
Exosomes are a heterogenous subpopulation of extracellular vesicles 30–150 nm in range
and of endosome-derived origin. We explored the exosome formation through different …

Spatiotemporal modulations in heterotypic condensates of prion and α-synuclein control phase transitions and amyloid conversion

A Agarwal, L Arora, SK Rai, A Avni… - Nature …, 2022 - nature.com
Biomolecular condensation via liquid-liquid phase separation of proteins and nucleic acids
is associated with a range of critical cellular functions and neurodegenerative diseases …

A new paradigm for diagnosis of neurodegenerative diseases: peripheral exosomes of brain origin

N Younas, LC Fernandez Flores, F Hopfner… - Translational …, 2022 - Springer
Neurodegenerative diseases are a heterogeneous group of maladies, characterized by
progressive loss of neurons. These diseases involve an intricate pattern of cross-talk …

Heterotypic electrostatic interactions control complex phase separation of tau and prion into multiphasic condensates and co-aggregates

SK Rai, R Khanna, A Avni… - Proceedings of the …, 2023 - National Acad Sciences
Biomolecular condensates formed via phase separation of proteins and nucleic acids are
thought to perform a wide range of critical cellular functions by maintaining spatiotemporal …

Extracellular vesicle transportation and uptake by recipient cells: A critical process to regulate human diseases

ZH Kwok, C Wang, Y Jin - Processes, 2021 - mdpi.com
Emerging evidence highlights the relevance of extracellular vesicles (EVs) in modulating
human diseases including but not limited to cancer, inflammation, and neurological …

[HTML][HTML] Extracellular vesicles, the emerging mirrors of brain physiopathology

A Cano, M Ettcheto, M Bernuz, R Puerta… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Extracellular vesicles are secreted by a wide variety of cells, and their primary functions
include intercellular communication, immune responses, human reproduction, and synaptic …