Engineered extracellular vesicles for bone therapy

Y Jiang, J Li, X Xue, Z Yin, K Xu, J Su - Nano Today, 2022 - Elsevier
Extracellular vesicles, which are secreted by living cells and play a critical role in cellular
communication, have emerged as a promising cell-free strategy in the treatment of many …

Adipose tissue stem cells meet preadipocyte commitment: going back to the future [S]

WP Cawthorn, EL Scheller, OA MacDougald - Journal of lipid research, 2012 - ASBMB
White adipose tissue (WAT) is perhaps the most plastic organ in the body, capable of
regeneration following surgical removal and massive expansion or contraction in response …

microRNA miR-27b impairs human adipocyte differentiation and targets PPARγ

M Karbiener, C Fischer, S Nowitsch… - Biochemical and …, 2009 - Elsevier
Obesity has emerged as a global health problem with more than 1.1 billion adults to be
classified as overweight or obese, and is associated with type 2 diabetes, cardiovascular …

Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach

AW Robert, BH Marcon, B Dallagiovanna… - Frontiers in cell and …, 2020 - frontiersin.org
Adipogenesis, osteogenesis and chondrogenesis of human mesenchymal stem/stromal
cells (MSC) are complex and highly regulated processes. Over the years, several studies …

Transplantation of adipose tissue and stem cells: role in metabolism and disease

TT Tran, CR Kahn - Nature Reviews Endocrinology, 2010 - nature.com
Humans and other mammals have three main adipose tissue depots: visceral white adipose
tissue, subcutaneous white adipose tissue and brown adipose tissue, each of which …

[HTML][HTML] miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells

H Li, T Li, S Wang, J Wei, J Fan, J Li, Q Han, L Liao… - Stem cell …, 2013 - Elsevier
Mesenchymal stem cells (MSCs) can differentiate into several distinct cell types, including
osteoblasts and adipocytes. The balance between osteogenic and adipogenic differentiation …

Activin a plays a critical role in proliferation and differentiation of human adipose progenitors

LE Zaragosi, B Wdziekonski, P Villageois… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Growth of white adipose tissue takes place in normal development and in
obesity. A pool of adipose progenitors is responsible for the formation of new adipocytes and …

The emerging role of exosomes in multiple myeloma

M Moloudizargari, M Abdollahi, MH Asghari, AA Zimta… - Blood Reviews, 2019 - Elsevier
Multiple myeloma (MM), one of the most prevalent hematological malignancies, accounts for
approximately 10% of all blood cancers. In spite of the recent advancements in MM therapy …

Elucidating the preadipocyte and its role in adipocyte formation: a comprehensive review

CN Sarantopoulos, DA Banyard, ME Ziegler… - Stem Cell Reviews and …, 2018 - Springer
Adipogenesis is a complex process whereby the multipotent adipose-derived stem cell is
converted to a preadipocyte before terminal differentiation into the mature adipocyte …

Differential gene expression profiling of human bone marrow-derived mesenchymal stem cells during adipogenic development

A Menssen, T Häupl, M Sittinger, B Delorme… - BMC genomics, 2011 - Springer
Background Adipogenesis is the developmental process by which mesenchymal stem cells
(MSC) differentiate into pre-adipocytes and adipocytes. The aim of the study was to analyze …