Insulin action is impaired in type 2 diabetes. The functions of the hormone are an integrated
product of insulin secretion from pancreatic β-cells and insulin clearance by receptor …

Knowledge of factors affecting variation in birth weight is especially important given the
relationship of birth weight to neonatal and adult health. The present study utilises two large …

The present study examines the effects of late vs. early gestation undernutrition on adult
glucose-insulin homeostasis in sheep and investigates whether the lower birth weight of …

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of reproductive-
aged women and is exacerbated by obesity. Exposure of ewes to excess testosterone (T) …

Prenatally testosterone (T)-treated female sheep exhibit ovarian and endocrinological
features that resemble those of women with polycystic ovarian syndrome (PCOS), which …

Most children who are short or light at birth due to intrauterine growth restriction (IUGR)
exhibit accelerated growth in infancy, termed “catch-up” growth, which together with IUGR …

Maternal undernutrition throughout pregnancy can have long-term effects on the health of
adult offspring. Undernutrition around the time of conception alters growth, metabolism, and …

In ruminants, prolonged exposure to high ambient temperatures negatively affects placental
development and function. The pursuing limitations in placental oxygen and nutrient supply …

Intrauterine growth restriction (IUGR) is associated with persistent metabolic complications,
but information is limited for IUGR infants. We determined glucose-stimulated insulin …

Key points Previous studies in fetuses with intrauterine growth restriction (IUGR) have
shown that adrenergic dysregulation was associated with low insulin concentrations and …