The bottom-up assembly of biological components in synthetic biology has contributed to a
better understanding of natural phenomena and the development of new technologies for …

RNA-based synthetic genetic circuits provide an alternative for traditional transcription-
based circuits in applications where genomic integration is to be avoided. Incorporating …

The potential of synthetic mRNA as a genetic carrier has increased its application in
scientific fields. Because the 5′ cap regulates the stability and translational activity of …

For regenerative cell therapies using pluripotent stem cell (PSC)-derived cells, large
quantities of purified cells are required. Magnetic-activated cell sorting (MACS) is a powerful …

Accurately characterizing cell types within complex cell structures provides invaluable
information for comprehending the cellular status during biological processes. In this study …

The ability to recognize molecular patterns is essential for the continued survival of
biological organisms, allowing them to sense and respond to their immediate environment …

MicroRNAs are short non-coding RNAs that are evolutionarily conserved and are pivotal
post-transcriptional mediators of gene regulation. Together with transcription factors and …

Human induced pluripotent stem cells (iPSCs) are promising cell resources for cell therapy
and drug discovery. However, iPSC-derived differentiated cells are often heterogenous and …

The reprogramming of somatic cells into induced pluripotent stem cells using Yamanaka
factors has revolutionized biomedical research. In the past few years, substantial advances …

Mammalian synthetic gene circuits have promise in biological and medical research due to
their capability of controlling cellular functions. Especially, post-transcriptional circuits are …