Reactive oxygen species (ROS) play a key role in the pathophysiological processes of a
wide range of renal diseases. Thus, antioxidants are expected to decrease the vulnerability …

Over the last decade, oxidative stress has been implicated in the pathogenesis of a wide
variety of seemingly unrelated renal diseases. Epidemiological studies have documented an …

Inflammation is associated with a number of chronic conditions, such as cancer and
cardiovascular disease. Reducing inflammation may help prevent or treat these conditions …

In inflammation, bacterial products and proinflammatory cytokines induce the formation of
large amounts of nitric oxide (NO) by inducible nitric oxide synthase (iNOS), and compounds …

The flavonoids comprise a large class of low-molecular-weight plant metabolites
ubiquitously distributed in food plants. These dietary antioxidants exert significant antitumor …

TLRs are conserved pattern recognition receptors that detect motifs of pathogens and host
material released during injury. For unknown reasons, renal TLR2 mRNA is mainly …

Background Volatile anesthetics protect against cardiac ischemia-reperfusion injury via
adenosine triphosphate-dependent potassium channel activation. The authors questioned …

Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal
tubular cell death. Background Tumor necrosis factor (TNF) receptor family members, such …

Several natural flavonoids have been demonstrated to perform some beneficial biological
activities, however, higher‐effective concentrations and poor‐absorptive efficacy in body of …

Flavonoids are widely distributed in plants, but their biological functions are still unclear. In
the present study, in vitro and in vivo experiments were performed to demonstrate the …