Physiological functions of threonine in animals: beyond nutrition metabolism

Q Tang, P Tan, N Ma, X Ma - Nutrients, 2021 - mdpi.com
Threonine (Thr), an essential amino acid for animals and the limiting amino acid in swine
and poultry diets, which plays a vital role in the modulation of nutritional metabolism …

Altered gut microbiome composition and function are associated with gut barrier dysfunction in healthy relatives of patients with Crohn's disease

H Leibovitzh, SH Lee, M Xue, JAR Garay… - Gastroenterology, 2022 - Elsevier
Background & Aims The gut microbiome has been suggested to play a role in gut barrier
hemostasis, but data are scarce and limited to animal studies. We therefore aimed to assess …

Immunomodulatory and biological properties of helminth-derived small molecules: Potential applications in diagnostics and therapeutics

K Yeshi, R Ruscher, A Loukas… - Frontiers in Parasitology, 2022 - frontiersin.org
Parasitic helminths secrete and excrete a vast array of molecules known to help skew or
suppress the host's immune response, thereby establishing a niche for sustained parasite …

[HTML][HTML] Diet rich in animal protein promotes pro-inflammatory macrophage response and exacerbates colitis in mice

K Kostovcikova, S Coufal, N Galanova… - Frontiers in …, 2019 - frontiersin.org
Diet is a major factor determining gut microbiota composition and perturbances in this
complex ecosystem are associated with the inflammatory bowel disease (IBD). Here, we …

Fecal microbiome alteration may be a potential marker for gastric cancer

J Wu, C Zhang, S Xu, C Xiang, R Wang… - Disease …, 2020 - Wiley Online Library
Although intestinal microbial dysbiosis was confirmed to be associated with many chronic
diseases and health status through complicated interaction with the host, the effect on …

Akkermansia muciniphila and Parabacteroides distasonis synergistically protect from colitis by promoting ILC3 in the gut

J Gaifem, A Mendes-Frias, M Wolter, A Steimle… - Mbio, 2024 - Am Soc Microbiol
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the
gastrointestinal tract. The etiology of IBD remains elusive, but the disease is suggested to …

Gut microbiome alterations in patients with thyroid nodules

A Li, T Li, X Gao, H Yan, J Chen, M Huang… - Frontiers in Cellular …, 2021 - frontiersin.org
Thyroid nodules are found in nearly half of the adult population. Accumulating evidence
suggests that the gut microbiota plays an important role in thyroid metabolism, yet the …

[HTML][HTML] Amino acids in piglet diarrhea: Effects, mechanisms and insights

X Zhou, J Liang, X Xiong, Y Yin - Animal Nutrition, 2024 - Elsevier
Piglet diarrhea is among one of the most serious health problems faced by the pig industry,
resulting in significant economic losses. Diarrheal disease in piglets has a multifactorial …

Dietary protein intake level modulates mucosal healing and mucosa-adherent microbiota in mouse model of colitis

S Vidal-Lletjós, M Andriamihaja, A Blais, M Grauso… - Nutrients, 2019 - mdpi.com
Mucosal healing after an inflammatory flare is associated with lasting clinical remission. The
aim of the present work was to evaluate the impact of the amount of dietary protein on …

Characteristics of fecal metabolic profiles in patients with irritable bowel syndrome with predominant diarrhea investigated using 1H‐NMR coupled with multivariate …

JS Lee, SY Kim, YS Chun, YJ Chun… - …, 2020 - Wiley Online Library
Background Gut microbiota are known to be closely related to irritable bowel syndrome
(IBS). However, not much is known about characteristic fecal metabolic profiles of IBS. We …