Iron homeostasis and ferroptosis in human diseases: mechanisms and therapeutic prospects
Iron, an essential mineral in the body, is involved in numerous physiological processes,
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …
[HTML][HTML] Ferroptosis and ferritinophagy in diabetes complications
Background With long-term metabolic malfunction, diabetes can cause serious damage to
whole-body tissue and organs, resulting in a variety of complications. Therefore, it is …
whole-body tissue and organs, resulting in a variety of complications. Therefore, it is …
[HTML][HTML] Diabetes and alpha lipoic acid
I Laher - Frontiers in pharmacology, 2011 - frontiersin.org
Diabetes mellitus is a multi-faceted metabolic disorder where there is increased oxidative
stress that contributes to the pathogenesis of this debilitating disease. This has prompted …
stress that contributes to the pathogenesis of this debilitating disease. This has prompted …
Antioxidants in the treatment of diabetes
Diabetes is a chronic metabolic disorder that continues to present as a major health problem
worldwide. It is characterized by absolute or relative deficiencies in insulin secretion and/or …
worldwide. It is characterized by absolute or relative deficiencies in insulin secretion and/or …
Effects of coenzyme Q10 supplementation on metabolic profile in diabetes: a systematic review and meta‐analysis
N Suksomboon, N Poolsup… - Journal of clinical …, 2015 - Wiley Online Library
What is known and objective CoenzymeQ10 (CoQ10), or ubiquinone, is an endogenous
enzyme cofactor produced by most human cells. It is a potent antioxidant and is necessary …
enzyme cofactor produced by most human cells. It is a potent antioxidant and is necessary …
Alpha-lipoic acid: An antioxidant with anti-aging properties for disease therapy
The anti-aging effects of alpha-lipoic acid (αLA), a natural antioxidant synthesized in human
tissues, have attracted a growing interest in recent years. αLA is a short-chain sulfur …
tissues, have attracted a growing interest in recent years. αLA is a short-chain sulfur …
Oxidative stress and mitochondrial dysfunction in Down syndrome
G Pagano, G Castello - Neurodegenerative Diseases, 2012 - Springer
Down syndrome (DS) or trisomy 21 is the genetic disease with highest prevalence
displaying phenotypic features that both include neurologic deficiencies and a number of …
displaying phenotypic features that both include neurologic deficiencies and a number of …
[PDF][PDF] Oxidative stress and Down syndrome. Do antioxidants play a role in therapy?
J Muchová, I Zitnanova… - Physiological …, 2014 - pdfs.semanticscholar.org
Oxidative stress is a phenomenon associated with imbalance between production of free
radicals and reactive metabolites (eg superoxide and hydrogen peroxide) and the …
radicals and reactive metabolites (eg superoxide and hydrogen peroxide) and the …
Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia
Background The mitochondrial cofactors α-lipoic acid (ALA), coenzyme Q10 (CoQ10) and
carnitine (CARN) play distinct and complementary roles in mitochondrial functioning, along …
carnitine (CARN) play distinct and complementary roles in mitochondrial functioning, along …
The effect of DASH diet on glycemic response, meta-inflammation and serum LPS in obese patients with NAFLD: a double-blind controlled randomized clinical trial
F Rooholahzadegan, S Arefhosseini, H Tutunchi… - Nutrition & …, 2023 - Springer
Background As dietary approaches to stop hypertension (DASH) dietary pattern has been
shown to be effective in hypertension and obesity, the present study investigated the effects …
shown to be effective in hypertension and obesity, the present study investigated the effects …