Pathophysiology of IBD associated diarrhea
AN Anbazhagan, S Priyamvada, WA Alrefai… - Tissue …, 2018 - Taylor & Francis
Inflammatory bowel diseases broadly categorized into Crohn's disease (CD) and ulcerative
colitis (UC), are chronic inflammatory disorders of the gastrointestinal tract with increasing …
colitis (UC), are chronic inflammatory disorders of the gastrointestinal tract with increasing …
[HTML][HTML] SLC9 gene family: function, expression, and regulation
H Xu, FK Ghishan, PR Kiela - Comprehensive Physiology, 2018 - ncbi.nlm.nih.gov
Abstract The Slc9 family of Na+/H+ exchangers (NHEs) plays a critical role in electroneutral
exchange of Na+ and H+ in the mammalian intestine as well as other absorptive and …
exchange of Na+ and H+ in the mammalian intestine as well as other absorptive and …
Minimal intestinal epithelial cell toxicity in response to short-and long-term food-relevant inorganic nanoparticle exposure
C McCracken, A Zane, DA Knight… - Chemical research in …, 2013 - ACS Publications
Toxicity of commercial nanoparticles of titania, silica, and zinc oxides is being investigated in
this in vitro study. Particles of these compositions are found in many food items, and thus this …
this in vitro study. Particles of these compositions are found in many food items, and thus this …
Tumor necrosis factor alpha reduces intestinal vitamin C uptake: a role for NF-κB-mediated signaling
VS Subramanian, S Sabui… - American Journal …, 2018 - journals.physiology.org
Sodium-dependent vitamin C transporter-1 (SVCT-1) is the major transporter mediating
intestinal vitamin C uptake. Intestinal inflammation and prolonged infection are associated …
intestinal vitamin C uptake. Intestinal inflammation and prolonged infection are associated …
The role of plasma membrane sodium/hydrogen exchangers in gastrointestinal functions: proliferation and differentiation, fluid/electrolyte transport and barrier integrity
K Nikolovska, UE Seidler, C Stock - Frontiers in Physiology, 2022 - frontiersin.org
The five plasma membrane Na+/H+ exchanger (NHE) isoforms in the gastrointestinal tract
are characterized by distinct cellular localization, tissue distribution, inhibitor sensitivities …
are characterized by distinct cellular localization, tissue distribution, inhibitor sensitivities …
Loss of Downregulated in Adenoma (DRA) Impairs Mucosal HCO3− Secretion in Murine Ileocolonic Inflammation
F Xiao, M Juric, J Li, B Riederer… - Inflammatory bowel …, 2012 - academic.oup.com
Background Ileocolonic luminal pH has been reported to be abnormally low in inflammatory
bowel disease (IBD) patients, and one of the causative factors may be reduced epithelial …
bowel disease (IBD) patients, and one of the causative factors may be reduced epithelial …
Pathophysiological role of ion channels and transporters in gastrointestinal mucosal diseases
Z Deng, Y Zhao, Z Ma, M Zhang, H Wang, Z Yi… - Cellular and Molecular …, 2021 - Springer
The incidence of gastrointestinal (GI) mucosal diseases, including various types of gastritis,
ulcers, inflammatory bowel disease and GI cancer, is increasing. Therefore, it is necessary to …
ulcers, inflammatory bowel disease and GI cancer, is increasing. Therefore, it is necessary to …
Activation of Nuclear Factor− κB by Tumor Necrosis Factor in Intestinal Epithelial Cells and Mouse Intestinal Epithelia Reduces Expression of the Chloride Transporter …
A Kumar, I Chatterjee, T Gujral, A Alakkam, H Coffing… - Gastroenterology, 2017 - Elsevier
Background & Aims Diarrhea associated with inflammatory bowel diseases has been
associated with increased levels of inflammatory cytokines, including tumor necrosis factor …
associated with increased levels of inflammatory cytokines, including tumor necrosis factor …
Role of epithelial ion transports in inflammatory bowel disease
D Magalhaes, JM Cabral… - American Journal of …, 2016 - journals.physiology.org
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with a complex
pathogenesis. Diarrhea is a highly prevalent and often debilitating symptom of IBD patients …
pathogenesis. Diarrhea is a highly prevalent and often debilitating symptom of IBD patients …
(Patho-)Physiology of Na+/H+ Exchangers (NHEs) in the Digestive System
L Cao, Z Yuan, M Liu, C Stock - Frontiers in physiology, 2020 - frontiersin.org
Na+/H+ exchangers (NHEs) are expressed in virtually all human tissues and organs. Two
major tasks of those NHE isoforms that are located in plasma membranes are cell volume …
major tasks of those NHE isoforms that are located in plasma membranes are cell volume …