Background: Common cancers develop through a multistep process often including inherited susceptibility. Collaboration among multiple institutions, and funding from multiple …
F Yuan, T Yuan, L Sui, Z Wang, Z Xi, Y Li, X Li… - Nature …, 2018 - nature.com
Carbon quantum dots (CQDs) have emerged as promising materials for optoelectronic applications on account of carbon's intrinsic merits of high stability, low cost, and …
JD McKay, RJ Hung, Y Han, X Zong… - Nature …, 2017 - nature.com
Although several lung cancer susceptibility loci have been identified, much of the heritability for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …
Background The influence of genetic variation on complex diseases is potentially mediated through a range of highly dynamic epigenetic processes exhibiting temporal variation during …
YV Sun, YJ Hu - Advances in genetics, 2016 - Elsevier
Complex and dynamic networks of molecules are involved in human diseases. High- throughput technologies enable omics studies interrogating thousands to millions of makers …
The methylome is subject to genetic and environmental effects. Their impact may depend on sex and age, resulting in sex-and age-related physiological variation and disease …
T Mazor, A Pankov, BE Johnson, C Hong, EG Hamilton… - Cancer cell, 2015 - cell.com
The evolutionary history of tumor cell populations can be reconstructed from patterns of genetic alterations. In contrast to stable genetic events, epigenetic states are reversible and …
Identifying methylation quantitative trait loci (meQTLs) and integrating them with disease- associated variants from genome-wide association studies (GWAS) may illuminate …
Background Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer and has a high risk of distant metastasis at every disease stage. We aimed to …