In vitro and in vivo model systems to study microbial biofilm formation

T Coenye, HJ Nelis - Journal of microbiological methods, 2010 - Elsevier
Biofilm formation is often considered the underlying reason why treatment with an
antimicrobial agent fails and as an estimated 65–80% of all human infections is thought to …

The cuticle

AP Page, IJ Johnstone - WormBook, 2007 - eprints.gla.ac.uk
The nematode cuticle is an extremely flexible and resilient exoskeleton that permits
locomotion via attachment to muscle, confers environmental protection and allows growth by …

[HTML][HTML] Metabolic control of hyaluronan synthases

D Vigetti, M Viola, E Karousou, G De Luca, A Passi - Matrix Biology, 2014 - Elsevier
Hyaluronan (HA) is a glycosaminoglycan composed by repeating units of D-glucuronic acid
(GlcUA) and N-acetylglucosamine (GlcNAc) that is ubiquitously present in the extracellular …

The worm has turned–microbial virulence modeled in Caenorhabditis elegans

CD Sifri, J Begun, FM Ausubel - Trends in microbiology, 2005 - cell.com
The nematode Caenorhabditis elegans is emerging as a facile and economical model host
for the study of evolutionarily conserved mechanisms of microbial pathogenesis and innate …

[HTML][HTML] Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms

JD de Oliveira, LS Carvalho, AMV Gomes… - Microbial cell …, 2016 - Springer
Hyaluronic acid, or HA, is a rigid and linear biopolymer belonging to the class of the
glycosaminoglycans, and composed of repeating units of the monosaccharides glucuronic …

A missense mutation in the bovine SLC35A3 gene, encoding a UDP-N-acetylglucosamine transporter, causes complex vertebral malformation

B Thomsen, P Horn, F Panitz, E Bendixen… - Genome …, 2006 - genome.cshlp.org
The extensive use of a limited number of elite bulls in cattle breeding can lead to rapid
spread of recessively inherited disorders. A recent example is the globally distributed …

[PDF][PDF] Signaling in the innate immune response

DH Kim - 2015 - dspace.mit.edu
The maintenance of cellular and organismal homeostasis in the face of changes in the
environment is essential for survival. Pathogenic microorganisms represent one type of …

Friend and foe: the two faces of Xenorhabdus nematophila

EE Herbert, H Goodrich-Blair - Nature Reviews Microbiology, 2007 - nature.com
Comparisons of mutualistic and pathogenic relationships are necessary to decipher the
common language of microorganism–host interactions, as well as the subtle differences in …

[HTML][HTML] Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans

H Schulenburg, MP Hoeppner, J Weiner III… - Immunobiology, 2008 - Elsevier
The nematode Caenorhabditis elegans has become an important model for the study of
innate immunity. Its immune system is based on several signaling cascades, including a Toll …

[HTML][HTML] Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses

J Begun, JM Gaiani, H Rohde, D Mack… - PLoS …, 2007 - journals.plos.org
Staphylococcus epidermidis and Staphylococcus aureus are leading causes of hospital-
acquired infections that have become increasingly difficult to treat due to the prevalence of …