The secret lives of mycobacteriophages
GF Hatfull - Advances in virus research, 2012 - Elsevier
The study of mycobacteriophages provides insights into viral diversity and evolution, as well
as the genetics and physiology of their pathogenic hosts. Genomic characterization of 80 …
as the genetics and physiology of their pathogenic hosts. Genomic characterization of 80 …
Molecular genetics of mycobacteriophages
GF Hatfull - Molecular genetics of mycobacteria, 2014 - Wiley Online Library
Mycobacteriophages are viruses that infect mycobacterial hosts including Mycobacterium
smegmatis and Mycobacterium tuberculosis. The first mycobacteriophages were isolated in …
smegmatis and Mycobacterium tuberculosis. The first mycobacteriophages were isolated in …
Purification and characterization of repressor of temperate S. aureus phage Φ11
To gain insight into the structure and function of repressor proteins of bacteriophages of
gram-positive bacteria, repressor of temperate Staphylococcus aureus phage ${\phi} 11 …
gram-positive bacteria, repressor of temperate Staphylococcus aureus phage ${\phi} 11 …
Repressor of temperate mycobacteriophage L1 harbors a stable C-terminal domain and binds to different asymmetric operator DNAs with variable affinity
Background Lysogenic mode of life cycle of a temperate bacteriophage is generally
maintained by a protein called'repressor'. Repressor proteins of temperate lambdoid phages …
maintained by a protein called'repressor'. Repressor proteins of temperate lambdoid phages …
DNA light-strand preferential recognition of human mitochondria transcription termination factor mTERF
Transcription termination of the human mitochondrial genome requires specific binding to
termination factor mTERF. In this study, mTERF was produced in E. coli and purified by two …
termination factor mTERF. In this study, mTERF was produced in E. coli and purified by two …
Regions and residues of an asymmetric operator DNA interacting with the monomeric repressor of temperate mycobacteriophage L1
Previously, the repressor protein of mycobacteriophage L1 bound to two operator DNAs with
dissimilar affinity. Surprisingly, the putative operator consensus sequence, 5 …
dissimilar affinity. Surprisingly, the putative operator consensus sequence, 5 …
Antagonistic effects Na+ and Mg2+ on the structure, function, and stability of mycobacteriophage L1 repressor
Temperate mycobacteriophage L1 encodes an unusual repressor (CI) for regulating its lytic-
lysogenic switching and, in contrast to the repressors of most temperate phages, it binds to …
lysogenic switching and, in contrast to the repressors of most temperate phages, it binds to …
Overexpression of a delayed early gene hlg1 of temperate mycobacteriophage L1 is lethal to both M. smegmatis and E. coli
Two genes of temperate mycobacteriophage L5, namely, gp63 and gp64, were
hypothesized to be toxic to M. smegmatis. An identical L5 gp64 ortholog (designated hlg1) …
hypothesized to be toxic to M. smegmatis. An identical L5 gp64 ortholog (designated hlg1) …
Thermal bioswitches and related genetic circuits, vectors, cells, compositions, methods and systems
2017-02-24 Assigned to CALIFORNIA INSTITUTE OF TECHNOLOGY reassignment
CALIFORNIA INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS INTEREST …
CALIFORNIA INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS INTEREST …
Effects of physical, ionic, and structural factors on the binding of repressor of mycobacteriophage L1 to its cognate operator DNA
To determine the factors influencing the binding of L1 repressor to its cognate operator DNA,
several gel shift as well as bioinformatic analyses have been carried out. The data show that …
several gel shift as well as bioinformatic analyses have been carried out. The data show that …