Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various
important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di …

Abstract About 2,500 papers dated 2014–2016 were recovered by searching the PubMed
database for Streptomyces, which are the richest known source of antibiotics. This review …

Root endophytes have been shown to have important roles in determining host fitness under
periods of drought stress, and yet the effect of drought on the broader root endosphere …

Volatile compounds emitted by bacteria are often sensed by other organisms as odours, but
their ecological roles are poorly understood,. Well-known examples are the soil-smelling …

With the increasingly dominant role of smartphones in our lives, mobile health care systems
integrating advanced point-of-care technologies to manage chronic diseases are gaining …

The ability to control the activity of CRISPR-dCas9 with precise spatiotemporal resolution
will enable tight genome regulation of user-defined endogenous genes for studying the …

The mycobacterial repressor, DarR, a TetR family regulator (TFR), was the first transcription
regulator shown to bind c-di-AMP. However, the molecular basis for this interaction and the …

Streptomycetes are highly metabolically gifted bacteria with the abilities to produce
bioproducts that have profound economic and societal importance. These bioproducts are …

Streptomyces are our principal source of antibiotics, which they generate concomitant with a
complex developmental transition from vegetative hyphae to spores. c-di-GMP acts as a …

Studies of transcriptional initiation in different bacterial clades reveal diverse molecular
mechanisms regulating this first step in gene expression. The WhiA and WhiB factors are …