Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …

Allergy is a major public health problem with a high socio‐economic impact. The number of
allergic patients is expected to reach to four billion within two decades when the World's …

Immune tolerance to both self-antigens and innocuous non–self-antigens is essential to
protect the host against chronic inflammatory diseases and tissue damage. A wide range of …

Regulatory B (Breg) cells have been shown to play a critical role in immune homeostasis
and in autoimmunity models. We have recently demonstrated that combined anti‐T cell …

Regulatory B cells (Bregs) ameliorate autoimmune disease and prevent allograft rejection.
Conversely, they hinder effective clearance of pathogens and malignancies. Breg activity is …

While B cells are traditionally known for their roles in antibody production, antigen
presentation and cytokine production, recent studies have highlighted the existence of B …

Renal ischemia-reperfusion injury (IRI) is a non-negligible clinical challenge for clinicians in
surgeries such as renal transplantation. Functional loss of renal tubular epithelial cell (TEC) …

Chronic graft-versus-host disease (cGVHD) is an increasingly frequent cause of morbidity
and mortality of allogeneic hematopoietic stem-cell transplantation. Sclerodermatous …

Our understanding of the role of B cells in organ transplantation remains incomplete and
continues to grow. The majority of research has focused on the detrimental role of antibodies …

Regulatory B cells contribute to the regulation of immune responses in cancer, autoimmune
disorders, allergic conditions and inflammatory diseases. Although most studies focus on …