In Vitro Comparison of Five Nebulizers During Noninvasive Ventilation: Analysis of Inhaled and Lost Doses

JB Michotte, E Jossen, J Roeseler, G Liistro… - Journal of aerosol …, 2014 - liebertpub.com
Background: Few studies on performance comparison of nebulizer systems coupled with a
single-limb circuit bilevel ventilator are available. Most of these data compared the aerosol …

Good practices for the laboratory performance testing of aqueous oral inhaled products (OIPs): an assessment from the international pharmaceutical aerosol …

JP Mitchell, I Carter, JD Christopher, M Copley… - AAPS …, 2023 - Springer
Multiple sources must be consulted to determine the most appropriate procedures for the
laboratory-based performance evaluation of aqueous oral inhaled products (OIPs) for the …

Development challenges and opportunities in aerosol drug delivery systems in non-invasive ventilation in adults

G Reychler, JB Michotte - Expert opinion on drug delivery, 2019 - Taylor & Francis
Introduction: With the gain in popularity of non-invasive ventilation (NIV), particularly in
patients requiring drug delivery by aerosol therapy, the feasibility of the combination …

That's cool!–Nebulization of thermolabile proteins with a cooled vibrating mesh nebulizer

S Hertel, T Pohl, W Friess, G Winter - European Journal of Pharmaceutics …, 2014 - Elsevier
Despite contrary reports, heating inside the medication reservoir was observed for several
vibrating mesh nebulizers, which may be detrimental when nebulizing biopharmaceuticals …

Effects of temperature and humidity on laser diffraction measurements to jet nebulizer and comparison with NGI

X Song, J Hu, S Zhan, R Zhang, W Tan - AAPS PharmSciTech, 2016 - Springer
Laser diffraction (LD) and next generation impactor (NGI) are commonly used for the
evaluation of inhaled drug formulations. In this study, the effect of temperature and humidity …

In Vitro Evaluation of Aerosol Delivery by Hand-Held Mesh Nebulizers in an Adult Spontaneous Breathing Lung Model

HY Tseng, HL Lin, HS Chiang - Journal of Aerosol Medicine and …, 2022 - liebertpub.com
Background: Drug inhalation is common mode of treatment for chronic obstructive
pulmonary disease (COPD). The aim of this study was to evaluate the efficiency of aerosol …

Pulmonary drug delivery following continuous vibrating mesh nebulization and inspiratory synchronized vibrating mesh nebulization during noninvasive ventilation in …

JB Michotte, E Staderini, AS Aubriot… - Journal of aerosol …, 2018 - liebertpub.com
Background: A breath-synchronized nebulization option that could potentially improve drug
delivery during noninvasive positive pressure ventilation (NIPPV) is currently not available …

[图书][B] Handbook for health care research

RL Chatburn - 2009 - books.google.com
Handbook for Health Care Research is included in the 2015 edition of the essential
collection of Doody's Core Titles. Doody's Book Review: 98-5 Stars! This is a unique book on …

Aerosol delivery to the lung is more efficient using an extension with a standard jet nebulizer than an open-vent jet nebulizer

L Pitance, G Reychler, T Leal, H Reychler… - Journal of aerosol …, 2013 - liebertpub.com
Background: Open-vent jet nebulizers are frequently used to promote drug deposition in the
lung, but their clinical efficacy and indications are not clear. Our study compared lung …

Pulmonary drug delivery systems for antimicrobial agents: facts and myths

ME Falagas, A Michalopoulos, EI Metaxas - International journal of …, 2010 - Elsevier
Inhaled antimicrobial agents are used for the treatment of respiratory tract infections due to
Gram-negative bacteria, mainly Pseudomonas aeruginosa. The effectiveness of the inhaled …