Design, synthesis, and mechanistic insight of novel imidazolones as potential EGFR inhibitors and apoptosis inducers
FG Abdulrahman, HS Abulkhair, HS El Saeed… - Bioorganic …, 2024 - Elsevier
As regards to the structural analysis and optimization of diverse potential EGFR inhibitors,
two series of imidazolyl-2-cyanoprop-2-enimidothioates and ethyl …
two series of imidazolyl-2-cyanoprop-2-enimidothioates and ethyl …
Synthesis, single crystal X-ray structure determination, Hirshfeld surface evaluation, void analysis, interaction energies, energy frameworks and density functional …
The current research work successfully presents facile synthesis, single crystal X-ray
structure determination, Hirshfeld surface (HS) analysis, and Density functional theory (DFT) …
structure determination, Hirshfeld surface (HS) analysis, and Density functional theory (DFT) …
Design, synthesis, in vitro anti-oxidant evaluation, α-amylase inhibition assay, and molecular docking analysis of 2-(2-benzylidenehydrazinyl)-4, 4-diphenyl-1H …
Reactive oxygen and nitrogen species (RONS) regulate physiological processes to ensure
cellular integrity. However, overproduction of RONS leads to oxidative stresses which results …
cellular integrity. However, overproduction of RONS leads to oxidative stresses which results …
New polymorph of N-benzoyl-morpholine-4-carbothioamide with ten crystallographically independent molecules in the asymmetric unit: Crystal structure, Hirshfeld …
Herein, facile synthesis, single crystal X-ray diffraction (SC-XRD) structure, Hirshfeld surface
(HS) analysis and Density functional theory (DFT) calculations of N-benzoyl-morpholine-4 …
(HS) analysis and Density functional theory (DFT) calculations of N-benzoyl-morpholine-4 …
N-Benzoyl-morpholine-4-carbothioamides: Crystal structures, Hirshfeld surface analysis, and Density functional theory calculations
The current research work describes facile synthesis, single crystal X-ray structures,
Hirshfeld surface (HS) analysis, and density functional theory (DFT) calculations of two N …
Hirshfeld surface (HS) analysis, and density functional theory (DFT) calculations of two N …