Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

One of the landmark events of the past 25 years in neuroscience research was the
establishment of neural stem cells (NSCs) as a life-long source of neurons and glia, a …

Antibiotics, though remarkably useful, can also cause certain adverse effects. We detected
that treatment of adult mice with antibiotics decreases hippocampal neurogenesis and …

Cortical growth and remodeling continues from birth through youth and adolescence to
stable adult levels changing slowly into senescence. There are critical periods of cortical …

Alcohol and substance abuse disorders involve continued use of substances despite
negative consequences, ie loss of behavioral control of drug use. The frontal-cortical areas …

Physically active lifestyles and other health-enhancing behaviors play an important role in
preserving executive function into old age. Conversely, emerging research suggests that …

The hippocampus is one of several limbic brain structures implicated in the pathophysiology
and treatment of mood disorders. Preclinical and clinical studies demonstrate that stress and …

The discovery that the adult mammalian brain creates new neurons from pools of stemlike
cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural …

Late adolescence (ie, 16–20 years of age) is a period characterized by escalation of
drinking and alcohol use problems for many and by the onset of an alcohol use disorder for …

Aims: This is a review of preclinical studies covering alcohol-induced brain neuronal death
and loss of neurogenesis as well as abstinence-induced brain cell genesis, eg brain …