Anthocyanins: Promising natural products with diverse pharmacological activities

J Liu, H Zhou, L Song, Z Yang, M Qiu, J Wang, S Shi - Molecules, 2021 - mdpi.com
Anthocyanins are natural products that give color to plants. As natural plant pigments,
anthocyanins also have a series of health-promoting benefits. Many researchers have …

Neuroprotective natural products for Alzheimer's disease

X Chen, J Drew, W Berney, W Lei - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …

Flavonoids as promising neuroprotectants and their therapeutic potential against Alzheimer's disease

T Minocha, H Birla, AA Obaid, V Rai… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is one of the serious and progressive neurodegenerative
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …

Anthocyanin as a therapeutic in Alzheimer's disease: A systematic review of preclinical evidences

S Suresh, RF Begum, A Singh, V Chitra - Ageing Research Reviews, 2022 - Elsevier
Background The aim of this systematic review is to ponder the possible mechanism of action
of anthocyanin in Alzheimer's disease (AD), to prompt the development of anthocyanin …

Bioactive compounds and their derivatives: an insight into prospective phytotherapeutic approach against alzheimer's disease

F Islam, JF Khadija, M Harun-Or-Rashid… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a common neurodegenerative brain disorder that causes
cellular response alterations, such as impaired cholinergic mechanism, amyloid‐beta (Aβ) …

Behind the scenes of anthocyanins—From the health benefits to potential applications in food, pharmaceutical and cosmetic fields

JS Câmara, M Locatelli, JAM Pereira, H Oliveira… - Nutrients, 2022 - mdpi.com
Anthocyanins are widespread and biologically active water-soluble phenolic pigments
responsible for a wide range of vivid colours, from red (acidic conditions) to purplish blue …

[HTML][HTML] Crosstalk among NLRP3 inflammasome, ETBR signaling, and miRNAs in stress-induced depression-like behavior: a modulatory role for SGLT2 inhibitors

RN Muhammad, LA Ahmed, RMA Salam, KA Ahmed… - …, 2021 - Elsevier
Depression is an overwhelming health concern, and many patients fail to optimally respond
to available standard therapies. Neuroplasticity and blood–brain barrier (BBB) integrity are …

Metabolites profiling, in-vitro and molecular docking studies of five legume seeds for Alzheimer's disease

RM Ibrahim, PM Abdel-Baki, OG Mohamed… - Scientific Reports, 2024 - nature.com
Even though legumes are valuable medicinal plants with edible seeds that are extensively
consumed worldwide, there is little information available on the metabolic variations …

Targeting inflammation by anthocyanins as the novel therapeutic potential for chronic diseases: An update

A Kozłowska, T Dzierżanowski - Molecules, 2021 - mdpi.com
Low-grade chronic inflammation (LGCI) and oxidative stress act as cooperative and
synergistic partners in the pathogenesis of a wide variety of diseases. Polyphenols …

Flavonoids bridging the gut and the brain: Intestinal metabolic fate, and direct or indirect effects of natural supporters against neuroinflammation and …

G Magni, B Riboldi, K Petroni, S Ceruti - Biochemical Pharmacology, 2022 - Elsevier
In recent years, experimental evidence suggested a possible role of the gut microbiota in the
onset and development of several neurodegenerative disorders, such as AD and PD, MS …