[HTML][HTML] Acute-on-chronic liver failure: Terminology, mechanisms and management

VK Br, SK Sarin - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Acute-on-chronic liver failure is an acute deterioration of liver function manifesting as
jaundice and coagulopathy with the development of ascites, with a high probability of …

Acute-on-chronic liver failure in chronic hepatitis B: an update

RH Zhao, Y Shi, H Zhao, W Wu… - Expert review of …, 2018 - Taylor & Francis
Introduction Acute-on-chronic liver failure is a common pattern of end-stage liver disease in
clinical practice and occurs frequently in patients with chronic hepatitis B or HBV-related …

Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update

SK Sarin, A Choudhury, MK Sharma, R Maiwall… - Hepatology …, 2019 - Springer
The first consensus report of the working party of the Asian Pacific Association for the Study
of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published …

Therapeutic plasma‐exchange improves systemic inflammation and survival in acute‐on‐chronic liver failure: a propensity‐score matched study from AARC

R Maiwall, M Bajpai, AK Choudhury, A Kumar… - Liver …, 2021 - Wiley Online Library
Abstract Background and Aim Plasma‐exchange (PE) has improved survival in acute liver
failure by ameliorating systemic inflammatory response syndrome (SIRS). We evaluated PE …

Management of acute-on-chronic liver failure: an algorithmic approach

SK Sarin, A Choudhury - Hepatology international, 2018 - Springer
Acute-on-chronic liver failure (ACLF) is a distinct syndrome of liver failure in a patient with
chronic liver disease presenting with jaundice, coagulopathy and ascites and/or hepatic …

Acute-on-chronic liver failure in China: rationale for developing a patient registry and baseline characteristics

W Gu, B Xu, X Zheng, J Chen, X Wang… - American Journal of …, 2018 - academic.oup.com
Definitions and descriptions of acute-on-chronic liver failure (ACLF) vary between Western
and Eastern types, and alcoholism and hepatitis B virus (HBV) are, respectively, the main …

Omega‐3 fatty acid lipid emulsions are safe and effective in reducing endotoxemia and sepsis in acute‐on‐chronic liver failure: an open‐label randomized controlled …

AV Kulkarni, L Anand, AK Vyas… - Journal of …, 2021 - Wiley Online Library
Abstract Background and Aim Sepsis is an important determinant of the outcome of acute‐
on‐chronic liver failure (ACLF) patients. Omega‐3 fatty acids (FAs) are known to suppress …

The role and mechanisms of macrophage polarization and hepatocyte pyroptosis in acute liver failure

D Xie, S Ouyang - Frontiers in immunology, 2023 - frontiersin.org
Acute liver failure (ALF) is a severe liver disease caused by disruptions in the body's
immune microenvironment. In the early stages of ALF, Kupffer cells (KCs) become depleted …

Plasma exchange in acute and acute on chronic liver failure

R Maiwall, SK Sarin - Seminars in Liver Disease, 2021 - thieme-connect.com
Liver failure in the context of acute (ALF) and acute on chronic liver failure (ACLF) is
associated with high mortality in the absence of a liver transplant. For decades, therapeutic …

Evaluation of prognostic values of inflammation-based makers in patients with HBV-related acute-on-chronic liver failure

J Cai, K Wang, T Han, H Jiang - Medicine, 2018 - journals.lww.com
Systemic inflammatory responses are associated with the development and progression of
liver failure. Neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR) …