Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Biocatalytic oxidation reactions: a chemist's perspective

JJ Dong, E Fernández‐Fueyo… - Angewandte Chemie …, 2018 - Wiley Online Library
Oxidation chemistry using enzymes is approaching maturity and practical applicability in
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …

Broadening the scope of biocatalysis in sustainable organic synthesis

RA Sheldon, D Brady - ChemSusChem, 2019 - Wiley Online Library
This Review is aimed at synthetic organic chemists who may be familiar with organometallic
catalysis but have no experience with biocatalysis, and seeks to provide an answer to the …

The hydrophobic effect applied to organic synthesis: recent synthetic chemistry “in water”

BH Lipshutz, S Ghorai… - Chemistry–A European …, 2018 - Wiley Online Library
Recent developments over the past few years in aqueous micellar catalysis are discussed.
Applications to problems in synthesis are highlighted, enabled by the use of surfactants that …

Directed evolution empowered redesign of natural proteins for the sustainable production of chemicals and pharmaceuticals

UT Bornscheuer, B Hauer, KE Jaeger… - Angewandte Chemie …, 2019 - Wiley Online Library
Directed evolution has advanced into a standard industrial “tool” to tailor naturally occurring
proteins for a variety of biotechnological applications, thus enabling product valorization and …

A retrosynthesis approach for biocatalysis in organic synthesis

ROMA de Souza, LSM Miranda… - … –A European Journal, 2017 - Wiley Online Library
For the planning of an organic synthesis route, the disconnection approach guided by
retrosynthetic analysis of possible intermediates and the chemical reactions involved, back …

Directed evolution of enzymes for industrial biocatalysis

JL Porter, RA Rusli, DL Ollis - ChemBioChem, 2016 - Wiley Online Library
Enzymes have the potential to catalyse a wide variety of chemical reactions. They are
increasingly being sought as environmentally friendly and cost‐effective alternatives to …

Synthetic biology—the synthesis of biology

S Ausländer, D Ausländer… - Angewandte Chemie …, 2017 - Wiley Online Library
Synthetic biology concerns the engineering of man‐made living biomachines from
standardized components that can perform predefined functions in a (self‐) controlled …

Biocatalysis with unnatural amino acids: enzymology meets xenobiology

F Agostini, JS Völler, B Koksch… - Angewandte Chemie …, 2017 - Wiley Online Library
The goal of xenobiology is to design biological systems endowed with unusual biochemical
functions, whereas enzymology concerns the study of enzymes, the workhorses of …

Enantioselective iodine (I/III) catalysis in organic synthesis

A Flores, E Cots, J Bergès… - Advanced Synthesis & …, 2019 - Wiley Online Library
Chiral aryliodine (III) reagents have provided an advanced concept for enantioselective
synthesis and catalysis. With the advent of chiral iodine (I/III) catalysis, many different …