Social determinants of health, health disparities, and adiposity

AS Baez, LR Ortiz-Whittingham, H Tarfa… - Progress in …, 2023 - Elsevier
Social determinants of health (SDoH), or the socioeconomic, environmental, and
psychosocial conditions in which individuals spend their daily lives, substantially influence …

Leisure-time sedentary behaviors are differentially associated with all-cause dementia regardless of engagement in physical activity

DA Raichlen, YC Klimentidis… - Proceedings of the …, 2022 - National Acad Sciences
Sedentary behavior (SB) is associated with cardiometabolic disease and mortality, but its
association with dementia is currently unclear. This study investigates whether SB is …

[HTML][HTML] Do associations between education and obesity vary depending on the measure of obesity used? A systematic literature review and meta-analysis

R Witkam, JM Gwinnutt, J Humphreys, J Gandrup… - SSM-population …, 2021 - Elsevier
Background Consistent evidence suggests a relationship between lower educational
attainment and total obesity defined using body mass index (BMI); however, a comparison of …

Higher adiposity and mental health: causal inference using Mendelian randomization

F Casanova, J O'Loughlin, S Martin… - Human molecular …, 2021 - academic.oup.com
Higher adiposity is an established risk factor for psychiatric diseases including depression
and anxiety. The associations between adiposity and depression may be explained by the …

Ancestry: How researchers use it and what they mean by it

B Dauda, SJ Molina, DS Allen, A Fuentes… - Frontiers in …, 2023 - frontiersin.org
Background: Ancestry is often viewed as a more objective and less objectionable population
descriptor than race or ethnicity. Perhaps reflecting this, usage of the term “ancestry” is …

Long-term cost-effectiveness of interventions for obesity: A mendelian randomisation study

S Harrison, P Dixon, HE Jones, AR Davies… - PLoS …, 2021 - journals.plos.org
Background The prevalence of obesity has increased in the United Kingdom, and reliably
measuring the impact on quality of life and the total healthcare cost from obesity is key to …

The causal association between obesity and primary open-angle glaucoma: a two-sample mendelian randomization study

Y Lin, X Zhu, W Luo, B Jiang, Q Lin, M Tang, X Li… - Frontiers in …, 2022 - frontiersin.org
The correlation between obesity and primary open-angle glaucoma (POAG) has not yet
been fully established. The aim of this study was to investigate the causal relationship …

Polygenic and socioeconomic risk for high body mass index: 69 years of follow-up across life

D Bann, L Wright, R Hardy, DM Williams… - PLoS …, 2022 - journals.plos.org
Genetic influences on body mass index (BMI) appear to markedly differ across life, yet
existing research is equivocal and limited by a paucity of life course data. We thus used a …

Genome-wide association study of occupational attainment as a proxy for cognitive reserve

H Ko, S Kim, K Kim, SH Jung, I Shim, S Cha, H Lee… - Brain, 2022 - academic.oup.com
Occupational attainment, which represents middle-age cognitive activities, is a known proxy
marker of cognitive reserve for Alzheimer's disease. Previous genome-wide association …

[HTML][HTML] Estimating the causal effect of liability to disease on healthcare costs using Mendelian Randomization

P Dixon, S Harrison, W Hollingworth, NM Davies… - Economics & Human …, 2022 - Elsevier
Accurate measurement of the effects of disease status on healthcare costs is important in the
pragmatic evaluation of interventions but is complicated by endogeneity bias. Mendelian …