Vascular smooth muscle cells and arterial stiffening: relevance in development, aging, and disease

P Lacolley, V Regnault, P Segers… - Physiological …, 2017 - journals.physiology.org
The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Modeling arterial pulse waves in healthy aging: a database for in silico evaluation of hemodynamics and pulse wave indexes

PH Charlton, J Mariscal Harana… - American Journal …, 2019 - journals.physiology.org
The arterial pulse wave (PW) is a rich source of information on cardiovascular (CV) health. It
is widely measured by both consumer and clinical devices. However, the physical …

Aging and arterial stiffness

HY Lee, BH Oh - Circulation Journal, 2010 - jstage.jst.go.jp
2258 LEE HY et al. inguinal region are barriers to its wide clinical use. In contrast, the
brachial–ankle PWV is easy to measure and has potential for screening purposes. In small …

Mechanical factors in arterial aging: a clinical perspective

MF O'rourke, J Hashimoto - Journal of the American College of Cardiology, 2007 - jacc.org
The human arterial system in youth is beautifully designed for its role of receiving spurts of
blood from the left ventricle and distributing this as steady flow through peripheral …

Effects of age and aerobic capacity on arterial stiffness in healthy adults.

PV Vaitkevicius, JL Fleg, JH Engel, FC O'Connor… - Circulation, 1993 - Am Heart Assoc
BACKGROUND It has been well established that arterial stiffness, manifest as an increase in
arterial pulse wave velocity or late systolic amplification of the carotid artery pressure pulse …

Noninvasive determination of age-related changes in the human arterial pulse.

R Kelly, C Hayward, A Avolio, M O'rourke - Circulation, 1989 - Am Heart Assoc
Arterial pressure waves were recorded noninvasively from the carotid, radial, femoral, or all
three of these arteries of 1,005 normal subjects, aged 2-91 years, using a new …

Clinical measurement of arterial stiffness obtained from noninvasive pressure waveforms

WW Nichols - American journal of hypertension, 2005 - academic.oup.com
Aortic pulse wave velocity (PWV) and augmentation index are independent predictors of
adverse cardiovascular events, including mortality. In hypertension and aging, central elastic …

Effective arterial elastance as index of arterial vascular load in humans.

RP Kelly, CT Ting, TM Yang, CP Liu, WL Maughan… - Circulation, 1992 - Am Heart Assoc
BACKGROUND This study tested whether the simple ratio of ventricular end-systolic
pressure to stroke volume, known as the effective arterial elastance (Ea), provides a valid …

Validation of a one-dimensional model of the systemic arterial tree

P Reymond, F Merenda, F Perren… - American Journal …, 2009 - journals.physiology.org
A distributed model of the human arterial tree including all main systemic arteries coupled to
a heart model is developed. The one-dimensional (1-D) form of the momentum and …

Assessment of vasoactive agents and vascular aging by the second derivative of photoplethysmogram waveform

K Takazawa, N Tanaka, M Fujita, O Matsuoka… - …, 1998 - Am Heart Assoc
To evaluate the clinical application of the second derivative of the fingertip
photoplethysmogram waveform, we performed drug administration studies (study 1) and …