Pyrimidines are aromatic heterocyclic compounds that contain two nitrogen atoms at
positions 1 and 3 of the six-membered ring. Numerous natural and synthetic pyrimidines are …

Nano-catalysts are of special character for the synthesis of organic molecules with high
efficiency, and exceptional physicochemical properties. The objective of this study was to …

This study was designed to determine the effectiveness of 5-(3-Hydroxybenzylidene)-2, 4, 6
(1H, 3H, 5H)-pyrimidinetrione (SR-5), 5-(4-Hydroxybenzylidene)-2, 4, 6 (1H, 3H, 5H) …

Biginelli reactions were performed using either ZrCl4 or ZrOCl2· 8H2O as catalysts under
neat conditions. Shorter reaction time than most of the classical methods was required when …

Abstract New leukotriene B4 (LTB4) antagonists have been synthesized that can be
considered as potential anti-inflammatory drugs. Structures containing the dioxygenated …

A novel series of 6‐acetyl‐[1, 2, 4] triazolo [1, 5‐a] pyrimidines, hexahydro‐[1, 2, 4] triazolo
[5, 1‐b] quinazolines, tetrahydrobenzo [4, 5] imidazo [2, 1‐b] quinazolin‐1‐ones, and 3 …

The synthetic utility of 2-mercaptonicotinonitriles 3 and 4, as well as 2-mercapto-4-oxo-6-
phenyl-1, 4-dihydropyrimidine-5-carbonitrile 20 as building blocks for novel bis-and poly …

Fused pyrimidines scaffolds such as pyrimidopyrimidines, purines and xanthines are
important structural motifs found in various natural products and drug molecules. They are …

Cardiac and hepatotoxicities are major concerns in the development of new drugs. Better
alternatives to other treatments are being sought to protect these vital organs from the …

The enaminone,(2E)-3-(dimethylamino)-1-(3, 4, 5-trimethoxyphenyl) prop-2-en-1-one was
prepared by refluxing 3, 4, 5-trimethoxy acetophenone with dimethylformamide …