The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …
physiological and pathological events in biology. Metal coordination chemistry, especially …
Ruthenium-nitrosyl complexes as NO-releasing molecules, potential anticancer drugs, and photoswitches based on linkage isomerism
I Stepanenko, M Zalibera, D Schaniel, J Telser… - Dalton …, 2022 - pubs.rsc.org
The synthesis of new types of mono-and polynuclear ruthenium nitrosyl complexes is driving
progress in the field of NO generation for a variety of applications. Light-induced Ru-NO …
progress in the field of NO generation for a variety of applications. Light-induced Ru-NO …
Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy
Soluble guanylate cyclase (sGC) is the primary receptor for nitric oxide (NO) in mammalian
nitric oxide signaling. We determined structures of full-length Manduca sexta sGC in both …
nitric oxide signaling. We determined structures of full-length Manduca sexta sGC in both …
Physiological activation and deactivation of soluble guanylate cyclase
BG Horst, MA Marletta - Nitric Oxide, 2018 - Elsevier
Soluble guanylate cyclase (sGC) is responsible for transducing the gaseous signaling
molecule nitric oxide (NO) into the ubiquitous secondary signaling messenger cyclic …
molecule nitric oxide (NO) into the ubiquitous secondary signaling messenger cyclic …
Structural perspectives on the mechanism of soluble guanylate cyclase activation
EC Wittenborn, MA Marletta - International journal of molecular sciences, 2021 - mdpi.com
The enzyme soluble guanylate cyclase (sGC) is the prototypical nitric oxide (NO) receptor in
humans and other higher eukaryotes and is responsible for transducing the initial NO signal …
humans and other higher eukaryotes and is responsible for transducing the initial NO signal …
Orthogonal spin labeling and pulsed dipolar spectroscopy for protein studies
Different types of spin labels are currently available for structural studies of biomolecules
both in vitro and in cells using Electron Paramagnetic Resonance (EPR) and pulse dipolar …
both in vitro and in cells using Electron Paramagnetic Resonance (EPR) and pulse dipolar …
Bio-inspired electrochemical detection of nitric oxide promoted by coordinating the histamine-iron phthalocyanine catalytic center on microelectrode
Biomimetic structures to fabricate bioelectronic interfaces that allow sensors to electrically
communicate with electrodes have potential applications in the development of biosensors …
communicate with electrodes have potential applications in the development of biosensors …
Metalloprotein enabled redox signal transduction in microbes
MT Williams, E Yee, GW Larson, EA Apiche… - Current opinion in …, 2023 - Elsevier
Microbes utilize numerous metal cofactor-containing proteins to recognize and respond to
constantly fluctuating redox stresses in their environment. Gaining an understanding of how …
constantly fluctuating redox stresses in their environment. Gaining an understanding of how …
[HTML][HTML] Structure/function of the soluble guanylyl cyclase catalytic domain
KC Childers, ED Garcin - Nitric Oxide, 2018 - Elsevier
Abstract Soluble guanylyl cyclase (GC-1) is the primary receptor of nitric oxide (NO) in
smooth muscle cells and maintains vascular function by inducing vasorelaxation in nearby …
smooth muscle cells and maintains vascular function by inducing vasorelaxation in nearby …
A new paradigm for gaseous ligand selectivity of hemoproteins highlighted by soluble guanylate cyclase
Nitric oxide (NO), carbon monoxide (CO), and oxygen (O 2) are important physiological
messengers whose concentrations vary in a remarkable range,[NO] typically from nM to …
messengers whose concentrations vary in a remarkable range,[NO] typically from nM to …