Applying the miniaturization technologies for biosensor design

B Derkus - Biosensors and Bioelectronics, 2016 - Elsevier
Microengineering technologies give us some opportunities in developing high-tech sensing
systems that operate with low volumes of samples, integrates one or more laboratory …

Two-photon endoscopy: state of the art and perspectives

V Kučikas, MP Werner, T Schmitz-Rode… - Molecular Imaging and …, 2021 - Springer
In recent years, the demand for non-destructive deep-tissue imaging modalities has led to
interest in multiphoton endoscopy. In contrast to bench top systems, multiphoton endoscopy …

Lissajous Scanning Two-photon Endomicroscope for In vivo Tissue Imaging

DY Kim, K Hwang, J Ahn, YH Seo, JB Kim, S Lee… - Scientific reports, 2019 - nature.com
An endomicroscope opens new frontiers of non-invasive biopsy for in vivo imaging
applications. Here we report two-photon laser scanning endomicroscope for in vivo cellular …

Integrated monolithic 3D MEMS scanner for switchable real time vertical/horizontal cross-sectional imaging

H Li, X Duan, Z Qiu, Q Zhou, K Kurabayashi… - Optics express, 2016 - opg.optica.org
We present an integrated monolithic, electrostatic 3D MEMS scanner with a compact chip
size of 3.2× 2.9 mm^ 2. Use of parametric excitation near resonance frequencies produced …

Handheld endomicroscope using a fiber-optic harmonograph enables real-time and in vivo confocal imaging of living cell morphology and capillary perfusion

K Hwang, YH Seo, DY Kim, J Ahn, S Lee… - Microsystems & …, 2020 - nature.com
Confocal laser endomicroscopy provides high potential for noninvasive and in vivo optical
biopsy at the cellular level. Here, we report a fully packaged handheld confocal …

MEMS-in-the-lens architecture for a miniature high-NA laser scanning microscope

T Liu, M Rajadhyaksha, DL Dickensheets - Light: Science & …, 2019 - nature.com
Laser scanning microscopes can be miniaturized for in vivo imaging by substituting optical
microelectromechanical system (MEMS) devices in place of larger components. The …

MEMS enabled miniature two-photon microscopy for biomedical imaging

X Yu, L Zhou, T Qi, H Zhao, H Xie - Micromachines, 2023 - mdpi.com
Over the last decade, two-photon microscopy (TPM) has been the technique of choice for in
vivo noninvasive optical brain imaging for neuroscientific study or intra-vital …

[HTML][HTML] The status of advanced imaging techniques for optical biopsy of colonic polyps

B Glover, J Teare, N Patel - Clinical and translational …, 2020 - journals.lww.com
The progressive miniaturization of photonic components presents the opportunity to obtain
unprecedented microscopic images of colonic polyps in real time during endoscopy. This …

MEMS-based two-photon microscopy with Lissajous scanning and image reconstruction under a feed-forward control strategy

X Zhang, Y Han, H Liu, X Xiao, Y Hu, Q Fu, L Feng… - Optics …, 2024 - opg.optica.org
Two-photon microscopy (TPM) based on two-dimensional micro-electro-mechanical
(MEMS) system mirrors shows promising applications in biomedicine and the life sciences …

Analysis of Error Sources in the Lissajous Scanning Trajectory Based on Two-Dimensional MEMS Mirrors

X Zhang, C Wang, Y Han, J Wang, Y Hu, J Wang, Q Fu… - Photonics, 2023 - mdpi.com
Deviations or distortions in the trajectoy of MEMS-based Lissajous scanning imaging
platforms might be detrimental to imaging quality. These deviations often arise from …