Traditional diagnostic systems went beyond empirical evidence on the structure of mental
health. Consequently, these diagnoses do not depict psychopathology accurately, and their …

Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous
drinking, defined by quantity and frequency of consumption, is associated with acute and …

The view that substance addiction is a brain disease, although widely accepted in the
neuroscience community, has become subject to acerbic criticism in recent years. These …

Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by
a combination of exaggerated incentive salience and habit formation, reward deficits and …

Alcohol is a major contributor to global disease and a leading cause of preventable death,
causing approximately 88,000 deaths annually in the United States alone. Alcohol use …

Research on psychopathy has progressed considerably in recent years against the
backdrop of important advances in the broader field of clinical psychological science. My …

Neuroadaptations that occur in response to repeated substance use diminish the euphoria
that is produced by the acute use of a drug and increase levels of physical and emotional …

Compulsive drug seeking that is associated with addiction is hypothesized to follow a
heuristic framework that involves three stages (binge/intoxication, withdrawal/negative affect …

The development of alcohol use disorder (AUD) involves binge or heavy drinking to high
levels of intoxication that leads to compulsive intake, the loss of control in limiting intake, and …

For decades, clinicians and researchers have recognized that borderline personality
disorder (BPD) and substance use disorders (SUDs) are often diagnosed within the same …