Gold-catalyzed synthesis of small rings

M Mato, A Franchino, C Garcı́a-Morales… - Chemical …, 2020 - ACS Publications
Three-and four-membered rings, widespread motifs in nature and medicinal chemistry, have
fascinated chemists ever since their discovery. However, due to energetic considerations …

Gold (I)-catalyzed activation of alkynes for the construction of molecular complexity

R Dorel, AM Echavarren - Chemical reviews, 2015 - ACS Publications
For centuries, gold had been considered a precious, purely decorative inert metal. It was not
until 1986 that Ito and Hayashi described the first application of gold (I) in homogeneous …

Organic reactions in microdroplets: reaction acceleration revealed by mass spectrometry

X Yan, RM Bain, RG Cooks - … Chemie International Edition, 2016 - Wiley Online Library
The striking finding that reaction acceleration occurs in confined‐volume solutions sets up
an apparent conundrum: Microdroplets formed by spray ionization can be used to monitor …

Expanding roles for lipid droplets

MA Welte - Current biology, 2015 - cell.com
Lipid droplets are the intracellular sites for neutral lipid storage. They are critical for lipid
metabolism and energy homeostasis, and their dysfunction has been linked to many …

Gold-catalyzed cyclopropanation reactions using a carbenoid precursor toolbox

D Qian, J Zhang - Chemical Society Reviews, 2015 - pubs.rsc.org
Homogeneous gold-catalyzed cyclopropanation has emerged as a powerful method in
organic synthesis due to its rich chemistry and fascinating reactivity. This thriving strategy is …

Gold carbene or carbenoid: is there a difference?

Y Wang, ME Muratore… - Chemistry–A European …, 2015 - Wiley Online Library
By reviewing the recent progress on the elucidation of the structure of gold carbenes and the
definitions of metal carbenes and carbenoids, we recommend to use the term gold carbene …

Atom-economic generation of gold carbenes: gold-catalyzed formal [3+ 2] cycloaddition between ynamides and isoxazoles

AH Zhou, Q He, C Shu, YF Yu, S Liu, T Zhao… - Chemical …, 2015 - pubs.rsc.org
The generation of gold carbenes via the gold-catalyzed intermolecular reaction of
nucleophiles containing relatively labile N–O or N–N bonds with alkynes has received …

Divergent synthesis of N-heterocycles via controllable cyclization of azido-diynes catalyzed by copper and gold

WB Shen, Q Sun, L Li, X Liu, B Zhou, JZ Yan… - Nature …, 2017 - nature.com
Gold-catalyzed intermolecular alkyne oxidation by an N–O bond oxidant has proven to be a
powerful method in organic synthesis during the past decade, because this approach would …

Zinc‐Catalyzed Alkyne Oxidation/C H Functionalization: Highly Site‐Selective Synthesis of Versatile Isoquinolones and β‐Carbolines

L Li, B Zhou, YH Wang, C Shu, YF Pan… - Angewandte Chemie …, 2015 - Wiley Online Library
An efficient zinc (II)‐catalyzed alkyne oxidation/C H functionalization sequence was
developed, thus leading to highly site‐selective synthesis of a variety of isoquinolones and β …

Hydration of unsymmetrical internal alkynes: factors governing the regioselectivity

X Liu, JL Pozzo, A Hamze, M Alami, O Provot - ACS Catalysis, 2023 - ACS Publications
Water addition on an unsymmetrical internal alkyne has significance in organic chemistry
and has stimulated challenging approaches to access a highly regioselective process …